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Bibliografia Linea Skin

- Cvetnić Z, Vladimir-Knezević S. Antimicrobial activity of grape fruit seed and pulp ethanolic extract. Acta Pharm. 2004; 54:243 -250

- Reagor L, et al. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: I. An in vitro agar assay. J Altern Complement Med. 2002; 8:325-332

- Huang ZR, et al. Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology. Molecules. 2009; 14:540-554

- Wolosik K, et al. The importance and perspective of plant-based squalene in cosmetology. J Cosmet Sci. 2013; 64:59-66

- Lodén M, Andersson AC. Effect of topically applied lipids on surfactant-irritated skin. Br J Dermatol. 1996; 134:215-220

- Ahmad Z. The uses and properties of almond oil. Complement Ther Clin Pract. 2010; 16:10-12

- McCusker MM, Grant-Kels JM. Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. Clin Dermatol. 2010; 28:440-451

- Payzar N, et al. A review of applications of tea tree oil in dermatology. Int J Dermatol. 2013; 52:784-790

- Dudonné S, et al. Phenolic composition and antioxidant properties of poplar bud (Populus nigra) extract: individual antioxidant contribution of phenolics and transcriptional effect on skin aging. J Agric Food Chem. 2011; 59:4527-4536

- Keen MA, Hassan I. Vitamin E in dermatology. Indian Dermatol Online J. 2016; 7:311-315

- Negro C, et al. Phenolic profile and antioxidant activity of Italian monovarietal Extra Virgin Olive Oils. Antioxidants 2019; 8: E161

- Kraft JN, Lynde CW. Moisturizers: what they are and a practical approach to product selection. Skin Therapy Lett. 2005; 10:1-8

- Yoo HK, et al. Lithospermum erythrorhizon extract protects keratinocytes and fibroblasts against oxidative stress. J Med Food. 2014; 17:1189-1196

- Chang MJ, et al. Cosmetic formulations containing Lithospermum erythrorhizon root extract show moisturizing effects on human skin. Arch Dermatol Res. 2008; 300:317-323

- Facino RM, et al. Echinacoside and caffeoyl conjugates protect collagen from free radical-induced degradation: a potential use of Echinacea extracts in the prevention of skin photodamage. Planta Med. 1995; 61:510-514
Elegami AA, et al. Two very unusual macrocyclic flavonoids from the water lily Nymphaea lotus. Phytochemistry. 2003; 63:727-731

- Dal’Belo SE, et al. Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. Skin Res Technol. 2006; 12:241-246

- West DP, Zhu YF. Evaluation of aloe vera gel gloves in the treatment of dry skin associated with occupational exposure. Am J Infect Control. 2003; 31:40-42

- Delatte SJ, et al. Effectiveness of beta-glucan collagen for treatment of partial-thickness burns in children. J Pediatr Surg. 2001; 36:113-118

- Kanlayavattanakul M, Lourith N. Biopolysaccharides for Skin Hydrating Cosmetics. Polysaccharides 2015; 60:1867-1892

- Chaiyana W, et al. Ocimum sanctum Linn. as a natural source of skin anti-ageing compounds. Ind Crops Prod 2019; 127: 217-224

- Garcia CSC, et al. Assessment of Salvia officinalis (L.) hydroalcoholic extract for possible use in cosmetic formulation as inhibitor of pathogens in the skin. Rev Cienc Farm Bas Aplic 2012; 33: 509-514

- Gianeti MD, et al. The use of green tea extract in cosmetic formulations:not only an antioxidant active ingredient. Dermatol Ther. 2013; 26:267-271

GSE COMPLEX BOOST INTEGRATORE

- Heggers JP, Cottingham J, Gusman J, Reagor L, McCoy L, Carino E, Cox R, Zhao JG. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. J Altern Complement Med. 2002 Jun; 8(3):333-40

- Cvetnić Z, Vladimir-Knezević S. Antimicrobial activity of grapefruit seed and pulp ethanolic extract. Acta Pharm. 2004 Sep; 54(3):243-50

- Zanotti Simões Dourado GK, de Abreu Ribeiro LC, Zeppone Carlos I, Borges César T. Orange Juice and Hesperidin Promote Differential Innate Immune Response in Macrophages ex vivo. Int J Vitam Nutr Res. 2013 Giugno; 83(3):162–7

- V. Verardo et al., “Bioactive Components in Fermented Foods and Food By-Products”, Foods 2020

- Verni, M.; Verardo, V.; Rizzello, C.G. How Fermentation Affects the Antioxidant Properties of Cereals and Legumes. Foods 2019.

- Doan, D.T.; Luu, D.P.; Nguyen, T.D.; Hoang Thi, B.; Pham Thi, H.M.; Do, H.N.; Luu, V.H.; Pham, T.D.; Than, V.T.; Pham Thi, H.H.; et al. “Isolation of Penicillium citrinum from Roots of Clerodendron cyrtophyllum and Application in Biosynthesis of Aglycone Isoflavones from Soybean Waste Fermentation”. Foods 2019

- Sevgili, A.; Erkmen, O. Improved Lycopene Production from Different Substrates by Mated Fermentation of Blakeslea Trispora. Foods 2019.

- Enbo Xu, Zhengzong Wu et al., “Calcium—lactate-induced enzymatic hydrolysis of extruded broken rice starch to improve Chinese rice wine fermentation and antioxidant capacity” Food Science and Technology, 2019.

- Mauro Fisberg e Rachel Machado “History of yogurt and current patterns of consumption”, Nutrition Reviews VR 2015.

- PDR, Physicians’ Desk Reference, CEC Editore, 2010

- Bhutta ZA ey al. Prevention of diarrhea and pneumonia in children in developing countries. J Pediatr. 1999

- Wapnir RA, Stiel et al. J Nutr, 1986

- D. Stamatiadis et al. Inhibition of 5α-reductase activity in human skin by zinc and azelaic acid. British J Dermatology, 1988

- Alan Leake at al. The effect of zinc on 5α-reduction of testosterone by the hyperplastic human prostate gland, Journal of Steroid Biochemistry 20(2):651-5, 1984

- Brigitte Dreno et al. Multicenter Randomized Comparative Double-Blind Controlled Clinical Trial of the Safety and Efficacy of Zinc Gluconate versus Minocycline Hydrochloride in the Treatment of Inflammatory Acne vulgaris. Dermatology 2001;203:135–140

- Maria Maares, Hajo Haase. A Guide to Human Zinc Absorption: General Overview and Recent Advances of In Vitro Intestinal Models. Nutrients 2020,

- Ananda S. Prasad. Zinc in human health: effect of zinc on immune cells. M O L M E D 2 0 0 8

- PDR, Physicians’ Desk Reference, CEC Editore, 2010

- Aleksandra Podgórska et al. Acne Vulgaris and Intake of Selected Dietary Nutrients—A Summary of Information, Healthcare 2021

- Mark G Rubin et al. Acne vulgaris, mental health and omega-3 fatty acids: a report of cases. Lipids in Health and Disease, 2008

- Youcef Mehdi et al. Selenium in the Environment, Metabolism and Involvement in Body Functions. Molecules, 2013

- G Michaëlsson, L E Edqvist. Erythrocyte glutathione peroxidase activity in acne vulgaris and the effect of selenium and vitamin E treatment . Acta Derm Venereol, 1984

- Haidar Hamid Al-Anbari et al.  Effects of silymarin, N-acetylcysteine and selenium in the treatment of papulopustular acne. Oxid Antioxid Med Sci. 2012

- R. Juhaszn e Toth. The role of selenium in nutrition. A review. Acta Univ. Sapientiae, Alimentaria, 11 (2018)

- David Benton. Selenium Intake, Mood and Other Aspects of Psychological Functioning. Nutritional Neuroscience, 2002 Vol. 5 (6), pp. 363–374

- Scott, B.H. The Effect of Selenium Supplementation on the Mood of Chronic Fatigue Syndrome and Healthy Control Subjects, M. Sc Thesis, University of Canterbury (New Zealand, 1993).

- M. Ferencik et al. Modulatory Effects of Selenium and Zinc on the Immune System. Folia Microbiol. 48 (3), 417–426 (2003)

- Sepideh Miraj et al. Pharmacological effect of Actium lappa: A review study, 2016

- Mohaddese Mahboubi  et al. Arctium Lappa and Management of Liver Functions to Detoxify the Bloodstream. The Natural Products Journal, 2020

- Assessment report on Arctium lappa L., radix EMA/HMPC/246764/2009

- Dandan Li et al. Prebiotic effectiveness of inulin extracted from edible burdock. Anaerobe 14 (2008)

- Akram Ahangarpour et al.  Effects of Arctium lappa aqueous extract on lipid profile and hepatic enzyme levels of sucrose-induced metabolic syndrome in female rats. Brazilian Journal of Pharmaceutical Sciences 2016.

- Valnet J. La Phytothérapie. Edition Le Livre de Poche, Vigot, Paris 2001; 164-166

- Malgorzata Miazga-Karska et al. Anti-Acne Action of Peptides Isolated from Burdock Root—Preliminary Studies and Pilot Testing. Molecules 2020

- Achermann, Y.; Goldstein, E.J.; Coenye, T.; Shirtli_, M.E. Propionibacterium acnes: From commensal to opportunistic biofilm-associated implant pathogen. Clin. Microbiol. Rev. 2014, 27, 419–440.

- Assessment report on Viola tricolor L. and/or subspecies Viola arvensis Murray (Gaud) and Viola vulgaris Koch (Oborny), herba cum flore EMA/HMPC/131735/2009

- Henry Leclerc, Lineamenti di fitoterapia, 1989

- 05 May 2021. EMA/HMPC/472964/2020. Committee on Herbal Medicinal Products (HMPC)

- Goetz P. Phytoaromatherapie de la furunculose. Phytotherapie 2017, 15: 297-299

- Gonçalves AFK, Friedrich RB, Boligon AA, Piana M, Beck RCR, Athayde ML. Anti-oxidant capacity, total phenolic contents and HPLC determination of rutin in Viola tricolor (L.) flowers. Free Rad Antiox 2012. 2 (4): 32-37

- German Commission E Monographs, Vol. 4, Bundesanzeiger nr. 50, 1986; Italian Edition by R. Longo, Studio Edizioni

- Zahra Khoshkam et al. The Study of Antimicrobial Activities of Partially Purified Cyclotide Content and Crude Extracts from Viola tricolor. J Med Bacteriol. 2016

- Naveed Muhammad et al. Ethnomedicinal, phytochemical and pharmacological profile of genus Viola. Phytopharmacology 2012

- Roland Hellinger et al. Immunosuppressive activity of an aqueous Viola tricolor herbal extract. J Ethnopharmacol. 2014

- M. Viuda-Martos et al. Pomegranate and its Many Functional Components as Related to Human Health: A Review. Vol.9, 2010, Comprehensive Reviews in Food Science and Food Safety.

- Seeram NP, Henning SM, Zhang Y, Suchard M, Li Z, Heber D.. Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 h. J. Nutr. 2006.

- Cerd´a B, et al. The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolized into bioavailable but poor antioxidant hydroxy-6H-dibenzopyran-6-one derivatives by the colonic microflora of healthy humans. Eur J Nutr 2004.

- Jung KH, Kim MJ, Ha E, Uhm YK, Kim HK, Chung JH, Yim SV. 2006. Suppressive effect of Punica granatum on the production of tumor necrosis factor (Tnf) in BV2 microglial cells. Biol Pharm Bull 29:1258–61.

- Ahmed S, Wang N, Hafeez BB, Cheruvu VK, Haqii TM. 2005. Punica granatum L. extract inhibits IL-1 beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro. J Nutr 135:2098–102.

- De Nigris F, Balestrieri ML, Williams-Ignarro S, D’Armiento FP, Fiorito C, Ignarro LJ, Napoli C. 2007. The influence of pomegranate fruit extract in comparison to regular pomegranate juice and seed oil on nitric oxide and arterial function in obese Zucker rats. Nitric Oxide 17:50–4.

- Larrosa M, et al. Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism. J Nut Biochem 2010.

- Kris Waldherr, Persephone and the Pomegranate: A Myth from Greece, 1993

- Tzulker R, Glazer I, Bar-Ilan I, Holland D, Aviram M, Amir R. Antioxidant activity, polyphenol content and related compounds in different fruit juices and homogenates prepared from 29 different pomegranate accessions. J Agric Food Chem 55:9559–70. 2007.

- Tezcan F, et al. Antioxidant activity and total phenolic, organic acid and sugar content in commercial pomegranate juices. Food Chem 115(3):873–7. 2009.

- Pacheco-Palencia et al. Protective effects of standardized pomegranate (Punica granatum L.) polyphenolic extract in ultraviolet-irradiated human skin fibroblasts. J Agric Food Chem 2008.

- Yoshimura M, Watanabe Y, Kasai K, Yamakoshi J, Koga T Inhibitory effect of an ellagic acid-rich pomegranate extracts on tyrosinase activity and ultraviolet-induced pigmentation. Biosci Biotechnol Biochem 69(12):2368–73. 2005

- Bialonska D, Kasimsetty SG, Schrader KK, Ferreira D. The effect of pomegranate (Punica granatum L.) byproducts and ellagitannins on the growth of human gut bacteria. J Agric Food Chem. 2009

- Antonio González-Sarrías et al. The endotoxemia marker lipopolysaccharide-binding protein is reduced in overweight-obese subjects consuming pomegranate extract by modulating the gut microbiota: a randomized clinical trial. Molecular Nutrition & Food Research, 2018

- Susanne M. Henning et al. Pomegranate Juice and Extract Consumption Increases the Resistance to UVB-induced Erythema and Changes the Skin Microbiome in Healthy Women: a Randomized Controlled Trial. Scientific Reports, 2019.

- Ahmed S, Wang N, Hafeez BB, Cheruvu VK andHaqqi TM. Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappa B in human chondrocytes in-vitro. Nutr, 2005.

- Hamid Reza Rahimi et al.  A Comprehensive Review of Punica granatum (Pomegranate) Properties inToxicological, Pharmacological, Cellular and Molecular Biology Researches,  Iranian Journal of Pharmaceutical Research (2012),

- Larrosa M, González-Sarrías A, Yáñez-Gascón MJ, Selma MV, Azorín-Ortuño M, Toti S, Tomás-Barberán F, Dolara P and Espín JC. Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism. J. Nutr. Biochem. (2010) 21: 717-725.

- Yunfeng Li et al. Evaluation of antioxidant properties of pomegranate peel extract in comparison with pomegranate pulp extract. Food Chemistry 96 2006.

- Ihsan E. A. Alsaimary. A chemotherapeutic efficacy of some antibiotics and Punica grantum L. extracts against Propionibacterium acnes isolated from acne vulgaris cases. Medical Journal of Islamic World Academy of Sciences, 2014

- Enzo Emanuele, M Biagi et al. Comparative effects of a fixed Polypodium leucotomos/Pomegranate combination versus Polypodium leucotomos alone on skin biophysical parameters. Neuroendocrinology Letters Volume 38 No. 1, 2017

- Iperpigmentazione post-infiammatoria: una revisione dell'epidemiologia, delle caratteristiche cliniche e delle opzioni di trattamento nella pelle di colore. E.C. Davis e V.D. Callender. J Clin Aesthet Dermatol. 2010 Jul; 3(7): 20-31

- Camilla Giuliani et al. Effects of Olive and Pomegranate By-Products on Human Microbiota: A Study Using the SHIME® In Vitro Simulator. Molecules 2019

- Dobroslawa Bialonska et al. The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota. International Journal of Food Microbiology 140 (2010)

- Weixi Liu,‡a Hang Ma et al. Pomegranate phenolics inhibit formation of advanced glycation endproducts by scavenging reactive carbonyl species. The Royal Society of Chemistry 2014

- Integrative Skin Science and Research, Oral Pomegranate Extract[SDC1]  on the Microbiome and Skin Biophysical Properties

- Nuggehally R. Srinivas, Is pomegranate juice a potential perpetrator of clinical drug–drug interactions? Review of the in vitro, preclinical and clinical evidence. Eur J Drug Metab Pharmacokinet, 2013.

- Shaikh Sameer D et al. Pharmacokinetic Drug Food Interaction Study of Nateglinide and Pomegranate Fruit Juice. IRANIAN JOURNAL OF DIABETES AND OBESITY, VOLUME 12, NUMBER 4, WINTER 2020

- Amirhossein Sahebkar et al. Effects of pomegranate juice on blood pressure: A systematic reviewand meta-analysis of randomized controlled trials. Pharmacological Research 115 (2017) 149–161

- Shakeri A, et al. Melissa officinalis L. – A review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol. 2016; 188:204-28

- Miraj S, et al. Melissa officinalis L: a review study with an antioxidant prospective. J Evid Based Complementary Altern Med. 2017; 22:385-394

- Mimica-Dukic N, et al. Antimicrobial and antioxidant activities of Melissa officinalis L. (Lamiaceae) essential oil. J Agric Food Chem. 2004; 52:2485-9

- Geuenich S, et al. Aqueous extracts from peppermint, sage and lemon balm leaves display potent anti-HIV-1 activity by increasing the virion density. Retrovirology 2008; 5:27

- Astani A, et al. Melissa officinalis extract inhibits attachment of herpes simplex virus in vitro. Chemotherapy. 2012; 58:70-7

- Chen SG, et al. Anti-enterovirus 71 activities of Melissa officinalis extract and its biologically active constituent rosmarinic acid. Sci Rep. 2017; 7:12264

- Martins EN, et al. Protective effect of Melissa officinalis aqueous extract against Mn-induced oxidative stress in chronically exposed mice. Brain Res Bull. 2012; 87:74-9

- Moacă EA, et al. A comparative study of Melissa officinalis lLeaves and stems ethanolic extracts in terms of antioxidant, cytotoxic, and antiproliferative potential. Evid Based Complement Alternat Med. 2018; 2018:7860456

- Guginski G, et al. Mechanisms involved in the antinociception caused by ethanolic extract obtained from the leaves of Melissa officinalis (lemon balm) in mice. Pharmacol Biochem Behav. 2009

- Hasanein P & Riahi H. Antinociceptive and antihyperglycemic effects of Melissa officinalis essential oil in an experimental model of diabetes. Med Princ Pract. 2015; 24:47-52

- Sforcin JM, et al. Lemongrass effects on IL-1beta and IL-6 production by macrophages. Nat Prod Res. 2009; 23:1151-9

- La Rocca V, et al. Geraniol Induces Antinociceptive Effect in Mice Evaluated in Behavioural and Electrophysiological Models. Basic Clin Pharmacol Toxicol. 2017; 120:22-29

- Savino F, et al. A randomized double-blind placebo-controlled trial of a standardized extract of Matricariae recutita, Foeniculum vulgare and Melissa officinalis (ColiMil) in the treatment of breastfed colicky infants. Phytother Res. 2005; 19:335-40

- Müller SF & Klement S. A combination of valerian and lemon balm is effective in the treatment of restlessness and dyssomnia in children. Phytomedicine. 2006; 13:383-7

- Gromball J, et al. Hyperactivity, concentration difficulties and impulsiveness improve during seven weeks' treatment with valerian root and lemon balm extracts in primary school children. Phytomedicine. 2014; 21: 1098-103

- Kennedy DO, et al. Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm). Psychosom Med. 2004; 66:607-1

- Cases J, et al. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances. Med J Nutrition Metab. 2011; 4:211-218

- Tavares-Silva C, et al. Homeopathic medicine of Melissa officinalis combined or not with Phytolacca decandra in the treatment of possible sleep bruxism in children: A crossover randomized triple-blinded controlled clinical trial. Phytomedicine. 2019; 58:152869

- Haybar H, et al. The effects of Melissa officinalis supplementation on depression, anxiety, stress, and sleep disorder in patients with chronic stable angina. Clin Nutr ESPEN. 2018; 26:47-52

- Zeraatpishe A, et al. Effects of Melissa officinalis L. on oxidative status and DNA damage in subjects exposed to long-term low-dose ionizing radiation. Toxicol Ind Health. 2011; 27:205-12

- Wölbling RH & Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine. 1994; 1:25-31

- Assessment report on Melissa officinalis L., folium EMA/HMPC/196746/2012

- Paul Posadzki et al. Herb–drug interactions: an overview of systematic reviews. British Journal of Clinical Pharmacology © 2012 The British Pharmacological Society.

 GSE COMPLEX MOUSSE DETERGENTE

- Heggers JP, Cottingham J, Gusman J, Reagor L, McCoy L, Carino E, Cox R, Zhao JG. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. J Altern Complement Med. 2002 Jun; 8(3):333-40

- Cvetnić Z, Vladimir-Knezević S. Antimicrobial activity of grapefruit seed and pulp ethanolic extract. Acta Pharm. 2004 Sep; 54(3):243-50

- Zanotti Simões Dourado GK, de Abreu Ribeiro LC, Zeppone Carlos I, Borges César T. Orange Juice and Hesperidin Promote Differential Innate Immune Response in Macrophages ex vivo. Int J Vitam Nutr Res. 2013 Giugno; 83(3):162–7

- V. Verardo et al., “Bioactive Components in Fermented Foods and Food By-Products”, Foods 2020

- Verni, M.; Verardo, V.; Rizzello, C.G. How Fermentation Affects the Antioxidant Properties of Cereals and Legumes. Foods 2019.

- Doan, D.T.; Luu, D.P.; Nguyen, T.D.; Hoang Thi, B.; Pham Thi, H.M.; Do, H.N.; Luu, V.H.; Pham, T.D.; Than, V.T.; Pham Thi, H.H.; et al. “Isolation of Penicillium citrinum from Roots of Clerodendron cyrtophyllum and Application in Biosynthesis of Aglycone Isoflavones from Soybean Waste Fermentation”. Foods 2019

- Sevgili, A.; Erkmen, O. Improved Lycopene Production from Different Substrates by Mated Fermentation of Blakeslea Trispora. Foods 2019.

- Enbo Xu, Zhengzong Wu et al., “Calcium—lactate-induced enzymatic hydrolysis of extruded broken rice starch to improve Chinese rice wine fermentation and antioxidant capacity” Food Science and Technology, 2019.

- Mauro Fisberg e Rachel Machado “History of yogurt and current patterns of consumption”, Nutrition Reviews VR 2015.

- Nassiri-Asl M, Hosseinzadeh H. Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Constituents: An Update. Phytother Res. 2016 Sep;30(9):1392-403.

- Mao QQ, Xu XY, Cao SY, Gan RY, Corke H, Beta T, Li HB. Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe). Foods. 2019 May 30;8(6):185.

- Upaganlawar A & Ghule B. Pharmacological Activities of Boswellia serrata Roxb. - Mini Review. Ethnobotanical Leaflets. 2009;6:10.

- Ammon HP. Boswellic Acids and Their Role in Chronic Inflammatory Diseases. Adv Exp Med Biol. 2016;928:291-327.

- El-Mostafa K, et al. Nopal cactus (Opuntia ficus-indica) as a source of bioactive compounds for nutrition, health and disease. Molecules. 2014; 19:14879-901

- Ammar I, et al. Variation in chemical composition and biological activities of two species of Opuntia flowers at four stages of flowering. J Food Sci Technol. 2017; 54:1502-1510

- Shoaib M, Shehzad A, Omar M, Rakha A, Raza H, Sharif HR, Shakeel A, Ansari A, Niazi S. Inulin: Properties, health benefits and food applications. Carbohydr Polym. 2016 Aug 20;147:444-454.

- Ahmed W, Rashid S. Functional and therapeutic potential of inulin: A comprehensive review. Crit Rev Food Sci Nutr. 2019;59(1):1-13.

- Kang HJ, Nam ES, Lee Y, Kim M. How Strong is the Evidence for the Anxiolytic Efficacy of Lavender?: Systematic Review and Meta-analysis of Randomized Controlled Trials. Asian Nurs Res (Korean Soc Nurs Sci). 2019 Dec;13(5):295-305.

- Malcolm BJ, Tallian K. Essential oil of lavender in anxiety disorders: Ready for prime time? Ment Health Clin. 2018 Mar 26;7(4):147-155

- Masago R, Matsuda T, Kikuchi Y, Miyazaki Y, Iwanaga K, Harada H, Katsuura T. Effects of inhalation of essential oils on EEG activity and sensory evaluation. J Physiol Anthropol Appl Human Sci. 2000 Jan;19(1):35-42.

- Shakeri A, Sahebkar A, Javadi B. Melissa officinalis L. - A review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol. 2016 Jul 21;188:204-28.

- Ballard CG, O'Brien JT, Reichelt K, Perry EK. Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa. J Clin Psychiatry. 2002 Jul;63(7):553-8.

- Huang L, Abuhamdah S, Howes MJ, Dixon CL, Elliot MS, Ballard C, Holmes C, Burns A, Perry EK, Francis PT, Lees G, Chazot PL. Pharmacological profile of essential oils derived from Lavandula angustifolia and Melissa officinalis with anti-agitation properties: focus on ligand-gated channels. J Pharm Pharmacol. 2008 Nov;60(11):1515-22. doi: 10.1211/jpp/60.11.0013. Erratum in: J Pharm Pharmacol. 2009 Feb;61(2):267.

- Mimica-Dukic N, Bozin B, Sokovic M, Simin N. Antimicrobial and antioxidant activities of Melissa officinalis L. (Lamiaceae) essential oil. J Agric Food Chem. 2004 May 5;52(9):2485-9.

- Schrader A, Siefken W, Kueper T, Breitenbach U, Gatermann C, Sperling G, Biernoth T, Scherner C, Stäb F, Wenck H, Wittern KP, Blatt T. Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin. Skin Pharmacol Physiol. 2012;25(4):192-9.

- Agre P, King LS, Yasui M, Guggino WB, Ottersen OP, Fujiyoshi Y, Engel A, Nielsen S. Aquaporin water channels--from atomic structure to clinical medicine. J Physiol. 2002 Jul 1;542(Pt 1):3-16.

- Agre P. The aquaporin water channels. Proc Am Thorac Soc. 2006;3(1):5-13.

- Sadava D, Heller HC, Orians GH, Purves WK, Hillis DM. Biologia, La scienza della vita. Zanichelli. 2010

- Rose WC (1949) Amino acid requirements of man. Fed Proc 8: 546–552.

- Fujiwara T, Kanazawa S, Ichibori R, Tanigawa T, Magome T, Shingaki K, Miyata S, Tohyama M, Hosokawa K. L-arginine stimulates fibroblast proliferation through the GPRC6A-ERK1/2 and PI3K/Akt pathway. PLoS One. 2014 Mar 20;9(3):e92168.

- Qin M, Landriscina A, Rosen JM, Wei G, Kao S, Olcott W, Agak GW, Paz KB, Bonventre J, Clendaniel A, Harper S, Adler BL, Krausz AE, Friedman JM, Nosanchuk JD, Kim J, Friedman AJ. Nitric Oxide-Releasing Nanoparticles Prevent Propionibacterium acnes-Induced Inflammation by Both Clearing the Organism and Inhibiting Microbial Stimulation of the Innate Immune Response. J Invest Dermatol. 2015 Nov;135(11):2723-2731.

- Baldwin H, Blanco D, McKeever C, Paz N, Vasquez YN, Quiring J, Enloe C, De León E, Stasko N. Results of a Phase 2 Efficacy and Safety Study with SB204, an Investigational Topical Nitric Oxide-releasing Drug for the Treatment of Acne Vulgaris. J Clin Aesthet Dermatol. 2016 Aug;9(8):12-8.

- Tunçez Akyürek F, Saylam Kurtipek G, Kurku H, Akyurek F, Unlu A, Abusoglu S, Ataseven A. Assessment of ADMA, IMA, and Vitamin A and E Levels in Patients with Acne Vulgaris. J Cosmet Dermatol. 2020 Dec;19(12):3408-3413.

- Ahmed AB, Adel M, Karimi P, Peidayesh M. Pharmaceutical, cosmeceutical, and traditional applications of marine carbohydrates. Adv Food Nutr Res. 2014;73:197-220.

- Johnson W Jr, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Andersen FA. Safety Assessment of Galactomannans as Used in Cosmetics. Int J Toxicol. 2015 Jul-Aug;34(1 Suppl):35S-65S.

GSE COMPLEX MASCHERA

- El-Mostafa K, et al. Nopal cactus (Opuntia ficus-indica) as a source of bioactive compounds for nutrition, health and disease. Molecules. 2014; 19:14879-901

- Ammar I, et al. Variation in chemical composition and biological activities of two species of Opuntia flowers at four stages of flowering. J Food Sci Technol. 2017; 54:1502-1510

- Tsilingiri K & Rescigno M. Postbiotics: what else? Benef Microbes 2013; 4:101-7

- Malashree L, et al. “Postbiotics” - One Step Ahead of Probiotics. Int J Curr Microbiol App. Sci 2019; 8: 2049-2053

- Meyer I, et al. How to mimic probiotics circumventig the hurdles of handling alive microorganisms? EuroCosmetics 2019; 6: 24-27

- Kezic S & Jakasa I. Filaggrin and Skin Barrier Function. Curr Probl Dermatol. 2016; 49:1-7

- Scartezzini, P.; Antognoni, F.; Raggi, M.A.; Poli, F.; Sabbioni, C. Vitamin C Content and Antioxidant Activity of the Fruit and of the Ayurvedic Preparation of Emblica officinalis Gaertn. J. Ethnopharmacol. 2006; 104, 113-118

- Kumar N, et al. 5ɑ-Reductase Inhibition and Hair Growth Promotion of Some Thai Plants Traditionally Used for Hair Treatment. J. Ethnopharmacol. 2012; 139:765-771

- Timodum T, et al.  Anti-Sebum Efficacy of Phyllanthus emblica L.E (Emblica) Toner on Facial Skin. Appl Sci. 2020; 10: 8193

- Khwandow K, et al. Potential Use of Amla Phyllanthus emblica L.) Fruit Extract to Protect Skin Keratinocytes from Inflammation and Apoptosis after UVB Irradiation. Antioxidants (Basel). 2021; 10:703

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- Peter Agre et al., “Aquaporin water channels – from atomic structure to clinical medicine”, Journal of Physiology (2002)

- Peter Agre “AQUAPORIN WATER CHANNELS”, Nobel Lecture, December 8, 2003

- Sadava, Heller, Orians, Purves, Hillis “BIOLOGIA LA SCIENZA DELLA VITA”  Zanichelli 2010

- Heggers JP, Cottingham J, Gusman J, Reagor L, McCoy L, Carino E, Cox R, Zhao JG. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. J Altern Complement Med. 2002 Jun; 8(3):333-40

- Cvetnić Z, Vladimir-Knezević S. Antimicrobial activity of grapefruit seed and pulp ethanolic extract. Acta Pharm. 2004 Sep; 54(3):243-50

- Zanotti Simões Dourado GK, de Abreu Ribeiro LC, Zeppone Carlos I, Borges César T. Orange Juice and Hesperidin Promote Differential Innate Immune Response in Macrophages ex vivo. Int J Vitam Nutr Res. 2013 Giugno; 83(3):162–7

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- Sevgili, A.; Erkmen, O. Improved Lycopene Production from Different Substrates by Mated Fermentation of Blakeslea Trispora. Foods 2019.

- Enbo Xu, Zhengzong Wu et al., “Calcium—lactate-induced enzymatic hydrolysis of extruded broken rice starch to improve Chinese rice wine fermentation and antioxidant capacity” Food Science and Technology, 2019.

- Mauro Fisberg e Rachel Machado “History of yogurt and current patterns of consumption”, Nutrition Reviews VR 2015.

- Raddatz-Mota D, Pérez-Flores LJ, Carrari F, Mendoza-Espinoza JA, de León-Sánchez FD, Pinzón-López LL, Godoy-Hernández G, Rivera-Cabrera F. Achiote (Bixa orellana L.): a natural source of pigment and vitamin E. J Food Sci Technol. 2017 May;54(6):1729-1741.

- Germano MP, de Pasquale R, Rapisarda A, Monteleone D, Keita A, Sanogo R. Drugs used in Africa as dyes: I. Skin absorption and tolerability of Bixa orellana L. Phytomedicine. 1997 Jun;4(2):129-31.

- Wertz PW. Lipids and barrier function of the skin. Acta Derm Venereol Suppl (Stockh). 2000; 208:7-11.

- Wertz PW. Lipids and the Permeability and Antimicrobial Barriers of the Skin. J Lipids. 2018; 2018:5954034

- Moreau RA, et al. Phytosterols and their derivatives: Structural diversity, distribution, metabolism, analysis, and health-promoting uses. Prog Lipid Res. 2018; 70:35-61

- BASF Care Creation. Phytosoothe - Natural protection for the physical and microbiotic skin barrier.

- Bojar R & Holland K. Review: the human cutaneous microflora and factors controlling colonisation. World J Microb Biotech 2002; 18:889–903

- Chen YE, et al. Skin microbiota-host interactions. Nature. 2018; 553:427-436

- Dréno B, et al. Microbiome in healthy skin, update for dermatologists. J Eur Acad Dermatol Venereol. 2016; 302038-2047

- Sanford JA & Gallo RL. Functions of the skin microbiota in health and disease. Semin Immunol. 2013; 25:370-7

- Christensen GJ, Brüggemann H. Bacterial skin commensals and their role as host guardians. Benef Microbes. 2014; 5:201-15

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- Malcolm BJ, Tallian K. Essential oil of lavender in anxiety disorders: Ready for prime time? Ment Health Clin. 2018 Mar 26;7(4):147-155

- Masago R, Matsuda T, Kikuchi Y, Miyazaki Y, Iwanaga K, Harada H, Katsuura T. Effects of inhalation of essential oils on EEG activity and sensory evaluation. J Physiol Anthropol Appl Human Sci. 2000 Jan;19(1):35-42.

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- Huang L, Abuhamdah S, Howes MJ, Dixon CL, Elliot MS, Ballard C, Holmes C, Burns A, Perry EK, Francis PT, Lees G, Chazot PL. Pharmacological profile of essential oils derived from Lavandula angustifolia and Melissa officinalis with anti-agitation properties: focus on ligand-gated channels. J Pharm Pharmacol. 2008 Nov;60(11):1515-22. doi: 10.1211/jpp/60.11.0013. Erratum in: J Pharm Pharmacol. 2009 Feb;61(2):267.

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- Ahmed AB, Adel M, Karimi P, Peidayesh M. Pharmaceutical, cosmeceutical, and traditional applications of marine carbohydrates. Adv Food Nutr Res. 2014;73:197-220.

- Johnson W Jr, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Andersen FA. Safety Assessment of Galactomannans as Used in Cosmetics. Int J Toxicol. 2015 Jul-Aug;34(1 Suppl):35S-65S.

 GSE COMPLEX RIBBON TIP

- Heggers JP, Cottingham J, Gusman J, Reagor L, McCoy L, Carino E, Cox R, Zhao JG. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. J Altern Complement Med. 2002 Jun; 8(3):333-40

- Cvetnić Z, Vladimir-Knezević S. Antimicrobial activity of grapefruit seed and pulp ethanolic extract. Acta Pharm. 2004 Sep; 54(3):243-50

- Zanotti Simões Dourado GK, de Abreu Ribeiro LC, Zeppone Carlos I, Borges César T. Orange Juice and Hesperidin Promote Differential Innate Immune Response in Macrophages ex vivo. Int J Vitam Nutr Res. 2013 Giugno; 83(3):162–7

- V. Verardo et al., “Bioactive Components in Fermented Foods and Food By-Products”, Foods 2020

- Verni, M.; Verardo, V.; Rizzello, C.G. How Fermentation Affects the Antioxidant Properties of Cereals and Legumes. Foods 2019.

- Doan, D.T.; Luu, D.P.; Nguyen, T.D.; Hoang Thi, B.; Pham Thi, H.M.; Do, H.N.; Luu, V.H.; Pham, T.D.; Than, V.T.; Pham Thi, H.H.; et al. “Isolation of Penicillium citrinum from Roots of Clerodendron cyrtophyllum and Application in Biosynthesis of Aglycone Isoflavones from Soybean Waste Fermentation”. Foods 2019

- Sevgili, A.; Erkmen, O. Improved Lycopene Production from Different Substrates by Mated Fermentation of Blakeslea Trispora. Foods 2019.

- Enbo Xu, Zhengzong Wu et al., “Calcium—lactate-induced enzymatic hydrolysis of extruded broken rice starch to improve Chinese rice wine fermentation and antioxidant capacity” Food Science and Technology, 2019.

- Mauro Fisberg e Rachel Machado “History of yogurt and current patterns of consumption”, Nutrition Reviews VR 2015.

- Raddatz-Mota D, Pérez-Flores LJ, Carrari F, Mendoza-Espinoza JA, de León-Sánchez FD, Pinzón-López LL, Godoy-Hernández G, Rivera-Cabrera F. Achiote (Bixa orellana L.): a natural source of pigment and vitamin E. J Food Sci Technol. 2017 May;54(6):1729-1741.

- Germano MP, de Pasquale R, Rapisarda A, Monteleone D, Keita A, Sanogo R. Drugs used in Africa as dyes: I. Skin absorption and tolerability of Bixa orellana L. Phytomedicine. 1997 Jun;4(2):129-31.

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- Peterson DM, Hahn MJ, Emmons CL. Oat avenanthramides exhibit antioxidant activities in vitro. Food Chem. 2002; 79(4):473–478.

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- Liu L, Zubik L, Collins FW, Marko M, Meydani M. The antiatherogenic potential of oat phenolic compounds. Atherosclerosis. 2004 Jul;175(1):39-49.

- Sur R, Nigam A, Grote D, Liebel F, Southall MD. Avenanthramides, polyphenols from oats, exhibit anti-inflammatory and anti-itch activity. Arch Dermatol Res. 2008 Nov;300(10):569-74.

- Landberg R, Sunnerheim K, Dimberg LH. Avenanthramides as lipoxygenase inhibitors. Heliyon. 2020 Jun 29;6(6):e04304.

- Cerio R, Dohil M, Jeanine D, Magina S, Mahé E, Stratigos AJ. Mechanism of action and clinical benefits of colloidal oatmeal for dermatologic practice. J Drugs Dermatol. 2010 Sep;9(9):1116-20.

- Alexandrescu DT, Vaillant JG, Dasanu CA. Effect of treatment with a colloidal oatmeal lotion on the acneform eruption induced by epidermal growth factor receptor and multiple tyrosine-kinase inhibitors. Clin Exp Dermatol. 2007 Jan;32(1):71-4.

- Ilnytska O, Kaur S, Chon S, Reynertson KA, Nebus J, Garay M, Mahmood K, Southall MD. Colloidal Oatmeal (Avena Sativa) Improves Skin Barrier Through Multi-Therapy Activity. J Drugs Dermatol. 2016 Jun 1;15(6):684-90.

- Castleman M; The Healing Herbs. The Ultimate Guide to the Curative Power of Nature's Medicines - Rodale Press 1991; pp. 42-44.

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- Tyler VE, et al. Pharmacognosy - Lea and Febiger 1981; pp. 61-63.

- Yagi A, et al. Cardiac stimulant action of constituents of Aloe Saponaria. J Pharm Sci. 1982; 71:739-41

- Esua MF, Rauwald JW. Novel bioactive maloyl glucans from aloe vera gel: isolation, structure elucidation and in vitro bioassays - Carbohydr Res. 2006; 341(3):355–64.

- Yagi A, Kabash A, Okamura N, Haraguchi H, Moustafa SM,Khalifa TI. Antioxidant, free radical scavenging and anti-inflammatory effects of aloesin derivatives in aloe vera Planta Med. 2002; 68:957-60.

- Wu JH, Xu C, Shan CY, Tan RX. Antioxidant properties and PC12 cell protective effects of APS-1, a polysaccharide from aloe vera var. chinensis. Life Sci. 2006; 78:622-3013

- Panahi Y, et al. Efficacy of Aloe vera/olive oil cream versus betamethasone cream for chronic skin lesions following sulfur mustard exposure: a randomized double-blind clinical trial. Cutan Ocul Toxicol. 2012 Jun; 31:95-103

- Davis RH, et al. Anti-inflammatory and wound healing activity of a growth substance in Aloe vera. J Am Podiatr Med Assoc. 1994; 84:77-81

- Yates KM, et al. Pilot study of the effect of acemannan in cats infected with feline immunodeficiency virus - Vet Immunonol Immunopathol 1992; 35:177-189

- Moon EJ, et al. A novel angiogenic factor derived from Aloe vera gel: beta-Sitosterol, a plant sterol. Angiogenesis 1999; 3: 117-123

- Choi SW, et al. The wound-healing effect of a glycoprotein fraction isolated from Aloe vera. Br J Dermatol 2001; 145:535-545

- Hashemi SA, et al. The Review on Properties of Aloe Vera in Healing of Cutaneous Wounds. Biomed Res Int 2015; 714216

- Teplicki E, et al. The Effects of Aloe vera on Wound Healing in Cell Proliferation, Migration, and Viability. Wounds. 2018; 30:263-268

- Rahmani N, et al. Effects of Aloe vera cream on chronic anal fissure pain, wound healing and hemorrhaging upon defection: a prospective double blind clinical trial. Eur Rev Med Pharmacol Sci 2014; 18:1078-84

- Sabzaligol M, et al. The effect of Aloevera gel on prineal pain & wound healing after episiotomy. Complem Med J Nurs Midwif. 2014; 4:766-75

- Syed TA, et al. Aloe vera extract 0.5% in hydrophilic cream versus Aloe vera gel for the management of genital herpes in males. A placebo-controlled, double-blind, comparative study. J Eur Acad Dermatol Venereol 1996; 7:294-5

- Maia Campos PMG, et al. Effects of Polysaccharide-Based Formulations on Human Skin. Polysaccharide, 2014; 1-18

- Dal'Belo SE, et al. Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. Skin Res Technol. 2006; 12:241-6.

- WHO Monographs on Selected Medicinal Plants - Volume 1. 1999; pp 43-49.

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- Fujiwara T, Kanazawa S, Ichibori R, Tanigawa T, Magome T, Shingaki K, Miyata S, Tohyama M, Hosokawa K. L-arginine stimulates fibroblast proliferation through the GPRC6A-ERK1/2 and PI3K/Akt pathway. PLoS One. 2014 Mar 20;9(3):e92168.

- Qin M, Landriscina A, Rosen JM, Wei G, Kao S, Olcott W, Agak GW, Paz KB, Bonventre J, Clendaniel A, Harper S, Adler BL, Krausz AE, Friedman JM, Nosanchuk JD, Kim J Friedman AJ. Nitric Oxide-Releasing Nanoparticles Prevent Propionibacterium acnes-Induced Inflammation by Both Clearing the Organism and Inhibiting Microbial Stimulation of the Innate Immune Response. J Invest Dermatol. 2015 Nov;135(11):2723-2731.

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- Tunçez Akyürek F, Saylam Kurtipek G, Kurku H, Akyurek F, Unlu A, Abusoglu S, Ataseven A. Assessment of ADMA, IMA, and Vitamin A and E Levels in Patients with Acne Vulgaris. J Cosmet Dermatol. 2020 Dec;19(12):3408-3413.

- Ahmed AB, Adel M, Karimi P, Peidayesh M. Pharmaceutical, cosmeceutical, and traditional applications of marine carbohydrates. Adv Food Nutr Res. 2014;73:197-220.

- Johnson W Jr, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Andersen FA. Safety Assessment of Galactomannans as Used in Cosmetics. Int J Toxicol. 2015 Jul-Aug;34(1 Suppl):35S-65S.

 GSE RI•DERM MANI

- Mathieu A, et al. Life on Human Surfaces: Skin Metagenomics. PLoS One. 2013; 8: e65288

- Larson E. Skin hygiene and infection prevention: more of the same or different approaches? Clin Infect Dis. 1999; 29:1287-94

- Eldmonds-Wilson SL, et al. Review of human hand microbiome research. J Dermatol Sci. 2015; 80:3-12

- Heggers JP, et al. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. J Altern Complement Med. 2002; 8:333-40

- Cvetnić Z & Vladimir-Knezević S. Antimicrobial activity of grapefruit seed and pulp ethanolic extract. Acta Pharm. 2004; 54:243-50

- Zanotti Simões Dourado GK, et al. Orange Juice and Hesperidin Promote Differential Innate Immune Response in Macrophages ex vivo. Int J Vitam Nutr Res. 2013; 83:162–7

- Parmar NS & Parmar S. Anti-ulcer potential of flavonoids. Indian J Physiol Pharmacol. 1998; 42:343-51

- Wertz PW. Lipids and barrier function of the skin. Acta Derm Venereol Suppl (Stockh). 2000; 208:7-11.

- Wertz PW. Lipids and the Permeability and Antimicrobial Barriers of the Skin. J Lipids. 2018; 2018:5954034

- Moreau RA, et al. Phytosterols and their derivatives: Structural diversity, distribution, metabolism, analysis, and health-promoting uses. Prog Lipid Res. 2018; 70:35-61

- BASF Care Creation. Phytosoothe - Natural protection for the physical and microbiotic skin barrier.

- Bojar R & Holland K. Review: the human cutaneous microflora and factors controlling colonisation. World J Microb Biotech 2002; 18:889–903

- Chen YE, et al. Skin microbiota-host interactions. Nature. 2018; 553:427-436

- Dréno B, et al. Microbiome in healthy skin, update for dermatologists. J Eur Acad Dermatol Venereol. 2016; 302038-2047

- Sanford JA & Gallo RL. Functions of the skin microbiota in health and disease. Semin Immunol. 2013; 25:370-7

- Christensen GJ, Brüggemann H. Bacterial skin commensals and their role as host guardians. Benef Microbes. 2014; 5:201-15

- Castleman M; The Healing Herbs. The Ultimate Guide to the Curative Power of Nature's Medicines - Rodale Press 1991; pp. 42-44.

- Ulbricht C, et al. An evidence-based systematic review of Aloe vera by the natural standard research collaboration - J Herb Pharmacother 2007; 7:279-323

- Tyler VE, et al. Pharmacognosy - Lea and Febiger 1981; pp. 61-63.

- Yagi A, et al. Cardiac stimulant action of constituents of Aloe Saponaria. J Pharm Sci. 1982; 71:739-41

- Esua MF, Rauwald JW. Novel bioactive maloyl glucans from aloe vera gel: isolation, structure elucidation and in vitro bioassays - Carbohydr Res. 2006; 341(3):355–64.

- Yagi A, Kabash A, Okamura N, Haraguchi H, Moustafa SM,Khalifa TI. Antioxidant, free radical scavenging and anti-inflammatory effects of aloesin derivatives in aloe vera Planta Med. 2002; 68:957-60.

- Wu JH, Xu C, Shan CY, Tan RX. Antioxidant properties and PC12 cell protective effects of APS-1, a polysaccharide from aloe vera var. chinensis. Life Sci. 2006; 78:622-3013

- Panahi Y, et al. Efficacy of Aloe vera/olive oil cream versus betamethasone cream for chronic skin lesions following sulfur mustard exposure: a randomized double-blind clinical trial. Cutan Ocul Toxicol. 2012 Jun; 31:95-103

- Davis RH, et al. Anti-inflammatory and wound healing activity of a growth substance in Aloe vera. J Am Podiatr Med Assoc. 1994; 84:77-81

- Yates KM, et al. Pilot study of the effect of acemannan in cats infected with feline immunodeficiency virus - Vet Immunonol Immunopathol 1992; 35:177-189

- Moon EJ, et al. A novel angiogenic factor derived from Aloe vera gel: beta-Sitosterol, a plant sterol. Angiogenesis 1999; 3: 117-123

- Choi SW, et al. The wound-healing effect of a glycoprotein fraction isolated from Aloe vera. Br J Dermatol 2001; 145:535-545

- Hashemi SA, et al. The Review on Properties of Aloe Vera in Healing of Cutaneous Wounds. Biomed Res Int 2015; 714216

- Teplicki E, et al. The Effects of Aloe vera on Wound Healing in Cell Proliferation, Migration, and Viability. Wounds. 2018; 30:263-268

- Panahi Y, Izadi M, Sayyadi N, Rezaee R, Jonaidi-Jafari N, Beiraghdar F, Zamani A, Sahebkar A. Comparative trial of Aloe vera/olive oil combination cream versus phenytoin cream in the treatment of chronic wounds. J Wound Care. 2015 Oct;24(10):459-60, 462-5

- Maia Campos PMG, et al. Effects of Polysaccharide-Based Formulations on Human Skin. Polysaccharide, 2014; 1-18

- Dal’Belo SE, Gaspar LR, Maia Campos PM. Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques - Skin Res Technol. 2006; 12:241–6

- West DP, Zhu YF. Evaluation of aloe vera gel gloves in the treatment of dry skin associated with occupational exposure - Am J Infect Control. 2003; 31:40–2

- WHO Monographs on Selected Medicinal Plants - Volume 1. 1999; pp 43-49

- Romana-Souza B & Monte-Alto-Costa A. Olive oil inhibits ageing signs induced by chronic stress in ex vivo human skin via inhibition of extracellular-signal-related kinase 1/2 and c-JUN pathways. Int J Cosmet Sci. 2019; 41:156-163

- Perugini P, et al. Efficacy of oleuropein against UVB irradiation: preliminary evaluation. Int J Cosmet Sci. 2008; 30:113-20

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- Salucci S, et al. Antioxidants in the prevention of UVB-induced keratynocyte apoptosis. J Photochem Photobiol B. 2014; 141:1-9

- Aparicio-Soto M, et al. Olive-Oil-Derived Polyphenols Effectively Attenuate Inflammatory Responses of Human Keratinocytes by Interfering with the NF-κB Pathway. Mol Nutr Food Res. 2019; 63: e1900019

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- Gavahian M, et al. Health benefits of olive oil and its components: Impacts on gut microbiota antioxidant activities, and prevention of noncommunicable diseases. Trends Food Sci Technol. 2019; 88:220-227

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- Sukumar S, Drízhal I. Hyaluronic acid and periodontitis. Acta Medica (Hradec Kralove). 2007; 50(4):225-8.

- Neuman MG, Nanau RM, Oruña L, Coto G. In vitro anti-inflammatory effects of hyaluronic acid in ethanol-induced damage in skin cells. J Pharm Pharm Sci. 2011; 14(3):425-37

GSE SIMIL-ONE®

- Chiu SC, Tsao SW, Hwang PI, Vanisree S, Chen YA, Yang NS; Differential functional genomic effects of anti-inflammatory phytocompounds on immune signaling - BMC Genomics. 2010 Sep 24; 11:513

- Yoo HG, Lee BH, Kim W, Lee JS, Kim GH, Chun OK, Koo SI, Kim DO; Lithospermum erythrorhizon extract protects keratinocytes and fibroblasts against oxidative stress - J Med Food  2014 Nov; 17(11):1189-96

- “Assessment report on Echinacea angustifolia DC., radix” – 27 Marzo 2012 EMA - Committee on Herbal Medicinal Products (HMPC)

- “Testo atlante di Fitoterapia” – Max Wichtl Ed. Italiana 2002 per UTET a cura di Roberto Della Loggia – pp. 179-182

- “Clinical Overview – Echinacea” - The ABC Clinical Guide to Herbs – pp. 85-96

- R. Maffei Facino et al.; Echinacoside and caffeoyl conjugates protect collagen from free radical-induced degradation: a potential use of Echinacea extracts in the prevention of skin photodamage – Planta Med; 61(1995)510

- Max Wichtl; Testo atlante di Fitoterapia - Ed. Italiana 2002 per UTET a cura di Roberto Della Loggia; pp. 179-182

- Akinjogunla OJ, Yah CS, Eghafona NO, Ogbemudia FO; Antibacterial activity of leave extracts of Nymphaea lotus (Nymphaeaceae) on Methicillin resistant Staphylococcus aureus (MRSA) and Vancomycin resistant Staphylococcus aureus (VRSA) isolated from clinical samples. Annals Biol Res. 2010; 1(2): 174-184

- Elegami AA, Bates C, Gray AI, Mackay SP, Skellern GG, Waigh RD; Two very unusual macrocyclic flavonoids from the water lily Nymphaea lotus – Phytochem; 2003; 63:727–31

- Afolayan AJ, Sharaibi OJ, Kazeem MI; Phytochemical Analysis and in-vitro Antioxidant Activity of Nymphaea lotus L. Int. J. Pharm. 2013;9:297–304

- Trease, GE, Evans WC. “Trease and Evans' Pharmacognosy 14th Ed.” W.B. Saunders Company Ltd., 1996; p. 612

- “Testo atlante di Fitoterapia” – Max Wichtl Ed. Italiana 2002 per UTET a cura di Roberto Della Loggia – pp. 179-182

- Chang M-J, Huang H-C, Chang H-C, Chang T-M; Cosmetic formulations containing  Lithospermum erythrorhizon root extract show moisturizing effects on human skin - Arch Dermatol Res. 2008; 300:317–323

- Esua MF, Rauwald JW. Novel bioactive maloyl glucans from aloe vera gel: isolation, structure elucidation and in vitro bioassays - Carbohydr Res. 2006; 341(3):355–64

- Wu JH,XuC, ShanCY, TanRX. Antioxidant properties and PC12 cell protective effects of APS-1, a polysaccharide from aloe vera var. chinensis - Life Sci. 2006; 78(6):622–30

- Choi, SW, Son, BW, Son, YS, Park, YI, Lee, SK and Chung, MH. The wound-healing effect of a glycoprotein fraction isolated from Aloe vera. Br J Dermatol 145, 2001; pp. 535-545

- Meadows TP. Aloe as a humectant in new skin preparations - Cosmetics Toiletries. 1980; 95:51-6

- Maia Campos PMG, de Melo MO, de Camargo Jr. FB. Effects of Polysaccharide-Based Formulations on Human Skin – Polysaccharide, 2014; pp. 1-18

- Wan Mohd Azizi, WS, Azad, AK, Ahmad NA, Sunzida NK; Clinical efficacy of aloe vera based products available in the market as skin moisturiser measured by tewl value and skin hydration level by using dermalab technology – Phar. Online vol. 2, 2016 – pp. 42-49

- Dal’Belo SE, Gaspar LR, Maia Campos PM. Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques - Skin Res Technol. 2006; 12:241–6

- West DP, Zhu YF. Evaluation of aloe vera gel gloves in the treatment of dry skin associated with occupational exposure - Am J Infect Control. 2003; 31:40–2

- Wei D, Williams D, Browder W - Activation of AP-1 and SP1 correlates with wound growth factor gene expression in glucan-treated human fibroblasts. Int Immunopharmacol 2002; 2:1163–1172.

- Babincová M, Bacová Z, Machová E, Kogan G - Antioxidant properties of carboxymethyl glucan: comparative analysis. J Med Food 2002; 5: 79–83.

- Zülli F, Suter F, Biltz H, Nissen HP. Improving skin function with CM-glucan, a biological response modifier from yeast - Int J Cosmet Sci 1998; 2:76–86.

- Pillai R, Redmond M, Roding J - Anti-wrinkle therapy: significant new findings in the non-invasive cosmetic treatment of skin wrinkles with beta-glucan. Int J Cosmet Sci 2005; 27: 292.

- Delatte SJ, Evans J, Hebra A, Adamson W, Othersen HB, Tagge EP. Effectiveness of beta glucan collagen for treatment of partial thickness burns in children - J Pediatr Surg 2001; 36: 113–118.

- García-Ochoa F1, Santos VE, Casas JA, Gómez E. Xanthan gum: production, recovery, and properties - Biotechnol Adv. 2000 Nov 1; 18(7):549-79.

- Kanlayavattanakul M, Lourith N. Biopolysaccharides for Skin Hydrating Cosmetics. Polysaccharides, 2015; pp 1867–1892

- Maia Campos PMG, de Melo MO, de Camargo Jr. FB. Effects of Polysaccharide-Based Formulations on Human Skin – Polysaccharide, 2014; pp. 1-18

- Pattanayak P, Behera P, Das D, Panda SK. Ocimum sanctum Linn. A reservoir plant for therapeutic applications: An overview. Pharmacogn Rev. 2010; 4(7):95-105

- Kelm MA, Nair MG, Stasburg GM, DeWitt DL. Antioxidant and cyclooxygenase inhibitiory phenolic compounds from Ocimum sanctum Linn.-  Phytomedicine 2000; 7:7-13

- Chaiyana W, Anuchapreeda S, Punyoyai C, Neimkhum W, Lee KH, Lin WC, Mueller M. Ocimum sanctum Linn. as a natural source of skin anti-ageing compounds - Industrial Crops and Products, 2019; 127, 217–224

- “Testo atlante di Fitoterapia” – Max Wichtl Ed. Italiana 2002 per UTET a cura di Roberto Della Loggia – pp. 538-542.

- Ghorbani A, Esmaeilizadeh M. Pharmacological properties of Salvia officinalis and its components - J Tradit Complement Med. 2017 Jan 13; 7(4):433-440

- Garcia CSC, Ely MR, Wasum RA, de Antoni Zoppa BC; Wollheim C, Neves GA, Weiss Angeli V, de Souza KCB. Assessment of Salvia officinalis (L.) hydroalcoholic extract  for possible use in cosmetic formulation as inhibitor of pathogens in the skin - J. of Basic and Applied Ph. Sc. Rev Ciênc Farm Básica 2012; 33(4):509-514

- Jocher A, Kessler S, Hornstein S, Schulte Mönting, J, Schempp, C M. The UV Erythema Test as a Model to Investigate the Anti-Inflammatory Potency of Topical Preparations – Reevaluation and Optimization of the Method. Skin Pharmacology and Physiology, 2005; 18(5), 234–240

- Reuter J, Jocher A, Hornstein S, Mönting JS, Schempp CM. Sage extract rich in phenolic diterpenes nhibits ultraviolet-induced erythema in vivo - Planta Med. 2007 Sep; 73(11):1190-1

- Baba S, Osakabe N, Natsume M, Yasuda A, Muto Y, Hiyoshi K, Takano H, Yoshikawa T, Terao

- J. Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla frutescens extract in humans – J. Eur J Nutr. 2005 Feb;44(1):1-9

- Zhou MW, Jiang RH, Kim KD, Lee JH, Kim CD, Yin WT, Lee JH. Rosmarinic acid inhibits poly(I:C)-induced inflammatory reaction of epidermal keratinocytes - Life Sci. 2016 Jun 15; 155:189-94

- Lembo S, Balato A, Di Caprio R, Cirillo T, Giannini V, Gasparri F, Monfrecola G. The modulatory effect of ellagic acid and rosmarinic acid on ultraviolet-B-induced cytokine/chemokine gene expression in skin keratinocyte (HaCaT) cells - Biomed Res Int. 2014; 2014:346793

- Hahn HJ, Kim KB, An IS, Ahn KJ, Han HJ.  Protective effects of rosmarinic acid against hydrogen peroxide‑induced cellular senescence and the inflammatory response in normal human dermal fibroblasts - Mol Med Rep. 2017 Dec; 16(6):9763-9769

- Fernando PM, Piao MJ, Kang KA, Ryu YS, Hewage SR, Chae SW, Hyun JW. Rosmarinic Acid Attenuates Cell Damage against UVB Radiation-Induced Oxidative Stress via Enhancing Antioxidant Effects in Human HaCaT Cells - Biomol Ther (Seoul). 2016 Jan; 24(1):75-84

- Lee J, Jung E, Koh J, Kim YS, Park D. Effect of rosmarinic acid on atopic dermatitis - J Dermatol. 2008 Dec; 35(12):768-71

GSE MYCOS

- Stephanie Dudonn_et al, “Phenolic Composition and Antioxidant Properties of Poplar Bud (Populus nigra) Extract: Individual Antioxidant Contribution of Phenolics and Transcriptional Effect on Skin Aging” American Chemical Society, 2011

- M. Keen et al., “Vitamin E in dermatology” Indian Dermatol Online J. 2016

- C. Negro, A. Aprile et al., “Phenolic Profile and Antioxidant Activity of Italian Monovarietal Extra Virgin Olive Oils” Antioxidants 2019

- J. N. Kraft “Moisturizers: What They Are and a Practical Approach to Product Selection”, Skin Therapy Letter, 2005

- M Lodén “The clinical benefit of moisturizers” JEADV, (2005)

- Vincent Hubiche  et al., “Flexible wax derivatives via polyglycerolysis”, Personal care, 2016

- N. Pazyar et al, “A review of applications of tea tree oil in dermatology”, The International Society of Dermatology, 2012

- Miloš Nikolic et al., “Screening of antimicrobial and antioxidant activity of commercial Melaleuca alternifolia (tea tree) essential oils”, Journal of Medicinal Plants Research, 2012

- Nader Pazyar et al., “A review of applications of tea tree oil in dermatology” The International Society of Dermatology, 2012

- C. F. Carson “Melaleuca alternifolia (Tea Tree) Oil: a Review of Antimicrobia land Other Medicinal Properties”, CLINICAL MICROBIOLOGY REVIEWS, 2006

- EMA “European Union herbal monograph on Melaleuca alternifolia (Maiden and Betch) Cheel, M. linariifolia Smith, M. dissitiflora F. Mueller and/or other species of Melaleuca, aetheroleum “2015

- E. Ernst A. Huntley, “Tea Tree Oil: A Systematic Review of Randomized Clinical Trials”, Research in Complementary Medicine, 2000.

GSE SKIN POWDER

- Heggers JP, Cottingham J, Gusman J, Reagor L, McCoy L, Carino E, Cox R, Zhao JG. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. J Altern Complement Med. 2002 Jun; 8(3):333-40

- Cvetnić Z, Vladimir-Knezević S. Antimicrobial Activity of grapefruit seed and pulp ethanolic extract. Acta Pharm. 2004 Sep; 54(3):243-50

- Han et al, "Bactericidal Activity of Grapefruit (Citrus Paradisi) Seed Extract-Based Disinfectant", Agric. Chem. Biotechnol. 49(3), 90-94 (2006)

- Gupta et al, "PHARMACOLOGICAL POTENTIALS OF CITRUS PARADISI - AN OVERVIEW", INTERNATIONAL JOURNAL OF PHYTOTHEARPY RESEARCH Volume 1 Issue 1 2011

- Zanotti Simões Dourado GK, de Abreu Ribeiro LC, Zeppone Carlos I, Borges César T. Orange Juice and Hesperidin Promote Differential Innate Immune Response in Macrophages ex vivo. Int J Vitam Nutr Res. 2013 Giugno; 83(3):162–7

- Cooke et al, "Olive Oil, Sunflower Oil or no Oil for Baby Dry Skin or Massage: A Pilot, Assessor-blinded, Randomized Controlled Trial (the Oil in Baby SkincaRE [OBSeRvE] Study)", Acta Derm Venereol 2016; 96: 323–330

- Danby et al, "Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care", Pediatric Dermatology Vol. 30 No. 1 42–50, 2013

GSE BABY DREAM

- Heggers JP, Cottingham J, Gusman J, Reagor L, McCoy L, Carino E, Cox R, Zhao JG. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. J Altern Complement Med. 2002 Jun; 8(3):333-40

- Cvetnić Z, Vladimir-Knezević S. Antimicrobial Activity of grapefruit seed and pulp ethanolic extract. Acta Pharm. 2004 Sep; 54(3):243-50

- Han et al, "Bactericidal Activity of Grapefruit (Citrus Paradisi) Seed Extract-Based Disinfectant", Agric. Chem. Biotechnol. 49(3), 90-94 (2006)

- Gupta et al, "PHARMACOLOGICAL POTENTIALS OF CITRUS PARADISI - AN OVERVIEW", INTERNATIONAL JOURNAL OF PHYTOTHEARPY RESEARCH Volume 1 Issue 1 2011

- Zanotti Simões Dourado GK, de Abreu Ribeiro LC, Zeppone Carlos I, Borges César T. Orange Juice and Hesperidin Promote Differential Innate Immune Response in Macrophages ex vivo. Int J Vitam Nutr Res. 2013 Giugno; 83(3):162–7

- Srivastava et al, "Chamomile: A herbal medicine of the past with bright future Janmejai K" Mol Med Report. 2010 November 1; 3(6): 895–901

- Mary E. Gerritsen, William W. Carley, Gerald E. Ranges, Chien-Ping Shen, Stacie A. Phan, Gwenda F. Ligon, and Carol A. Perry, "Flavonoids Inhibit Cytokine-Induced Endothelial Cell Adhesion Protein Gene Expression" AmerlcanJournal of Pathology, Vol. 147 Vo 2, Alogotst 1995

- Elisabetta Bigagli, Lorenzo Cinci, Mario D'Ambrosio, Cristina Luceri , Pharmacological activities of an eye drop containing Matricaria chamomilla and Euphrasia officinalis extracts in UVB-induced oxidative stress and inflammation of human corneal cells, Journal of Photochemistry & Photobiology, B: Biology (2017)

- Kolodziejczyk-Czepas et al, "Radical scavenging and antioxidant effects of Matricaria chamomillapolyphenolic–polysaccharide conjugates", International Journal of Biological Macromolecules 72 (2015) 1152–1158

- Korting et al, "Anti-inflammatory activity of hamamelis distillate applied topically to the skin", Eur J Clin Pharmacol (1993) 44:315-318

- Smolinski A, Pestka J, "Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb1 (ginseng) and parthenolide (feverfew)", Food and Chemical Toxicology 41 (2003) 1381–1390

- Zitterl-Eglseer et al, "Anti-oedematous activities of the main triterpendiol esters of marigold (Calendula officinalis L.)", Journal of Ethnopharmacology 57 (1997) 139–144

- Gazim et al, "Analysis of the essential oils from Calendula officinalis growing in Brazil using three different extraction procedures" Brazilian Journal of Pharmaceutical Sciences vol. 44, n. 3, jul./set., 2008

- BP Muley*, SS Khadabadi and NB Banarase, "Phytochemical Constituents and Pharmacological Activities of Calendula officinalis Linn (Asteraceae): A Review" Trop J Pharm Res, October 2009; 8 (5): 4 55

- Re et al, "Application of the threshold of toxicological concern approach for the safety evaluation of calendula flower (Calendula officinalis) petals and extracts used in cosmetic and personal care products", Food and Chemical Toxicology 47 (2009) 1246–1254

- Marks, Jr, Ronald C. Shank, Thomas J. Slaga and Paul W. Snyder F. Alan Andersen, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G., "Calendula officinalis-Derived Cosmetic Ingredients Final Report of the Cosmetic Ingredient Review Expert Panel Amended Safety Assessment of Calendula officinalis-Derived Cosmetic Ingredients", International Journal of Toxicology 2010 29: 221S

- AKHTAR et al, "CALENDULA EXTRACT: EFFECTS ON MECHANICAL PARAMETERS OF HUMAN SKIN", Acta Poloniae Pharmaceutica ñ Drug Research, Vol. 68 No. 5 pp. 693ñ701, 2011

- Cooke et al, "Olive Oil, Sunflower Oil or no Oil for Baby Dry Skin or Massage: A Pilot, Assessor-blinded, Randomized Controlled Trial (the Oil in Baby SkincaRE [OBSeRvE] Study)", Acta Derm Venereol 2016; 96: 323–330

- Danby et al, "Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care", Pediatric Dermatology Vol. 30 No. 1 42–50, 2013

GSE READY SPRAY

- Heggers JP, Cottingham J, Gusman J, Reagor L, McCoy L, Carino E, Cox R, Zhao JG. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. J Altern Complement Med. 2002 Jun; 8(3):333-40

- Cvetnić Z, Vladimir-Knezević S. Antimicrobial Activity of grapefruit seed and pulp ethanolic extract. Acta Pharm. 2004 Sep; 54(3):243-50

- Han et al, "Bactericidal Activity of Grapefruit (Citrus Paradisi) Seed Extract-Based Disinfectant", Agric. Chem. Biotechnol. 49(3), 90-94 (2006)

- Gupta et al, "PHARMACOLOGICAL POTENTIALS OF CITRUS PARADISI - AN OVERVIEW", INTERNATIONAL JOURNAL OF PHYTOTHEARPY RESEARCH Volume 1 Issue 1 2011

- Zanotti Simões Dourado GK, de Abreu Ribeiro LC, Zeppone Carlos I, Borges César T. Orange Juice and Hesperidin Promote Differential Innate Immune Response in Macrophages ex vivo. Int J Vitam Nutr Res. 2013 Giugno; 83(3):162–7

- Sahu et al, "Inhibition of Complement by Covalent Attachment of Rosmarinic Acid to Activated C3b", Biochemical Pharmacology, Vol. 57, pp. 1439–1446, 1999

- Lee et al, "Rosmarinic acid as a downstream inhibitor of IKK-b in TNF-a-induced upregulation of CCL11 and CCR3", British Journal of Pharmacology (2006) 148, 366–375

- Zdenka KRAJČOVIČOVÁ, Vladimír MELUŠ, "BIOACTIVITY AND POTENTIAL HEALTH BENEFITS OF ROSMARINIC ACID Minireview", University Review, Vol. 7, 2013, No. 2, p. 8-14

- Aburjai et al, "Ethnopharmacological survey of medicinal herbs in Jordan, the Ajloun Heights region", Journal of Ethnopharmacology 110 (2007) 294–304

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