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Bibliografia Linea Insufficienza Venosa

 
waVEN Spray 50 ml


 
 
- Duckstein SM, Stintzing FC. Investigation on the phenolic constituents in Hamamelis virginiana leaves by HPLC-DAD and LC-MS/MS. Anal Bioanal Chem. 2011 Aug; 401(2):677-88.

- Cosmetic Ingredient Review. Safety Assessment of Hamamelis virginiana (Witch Hazel)-Derived Ingredients as Used in Cosmetics. June 7, 2018.

- WHO Monographs on Selected Medicinal Plants. Folium et Cortex Hamamelidis. Vol. 2; pp. 124-136.

- Deters A, Dauer A, Schnetz E, Fartasch M, Hensel A. High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin. Phytochemistry. 2001 Nov; 58(6):949-58.

- Sorkin B. Hametumsalbe, eine kortikoidfreie antiinflammatorische Salbe. Physikalische Medizin und Rehabilitation. 1980; 21:53-57.

- Masaki H, Atsumi T, Sakurai H. Evaluation of superoxide scavenging activities of hamamelis extract and hamamelitannin. Free Radic Res Commun.1993;19(5):333-40.

- Masaki H, Atsumi T, Sakurai H. Hamamelitannin as a new potent active oxygen scavenger. Phytochemistry. 1994; 37:337-343.

- Habtemariam S. Hamamelitannin from Hamamelis virginiana inhibits the tumour necrosis factor-alpha (TNF)-induced endothelial cell death in vitro. Toxicon. 2002; 40(1):83-88.

- Moore W, James DK. A random trial of three topical analgesic agents in the treatment of episiotomy pain following instrumental vaginal delivery. Journal of Obstetrics and Gynaecology. 1989. 10:35-39.

- Diemunsch AM, Mathis C. S.T.P. Effet vasoconstricteur de l’hamamélis en application externe. Pharma; 1987. 3:111-114.

- Kubica P, Szopa A, Dominiak J, Luczkiewicz M, Ekiert H. Verbena officinalis (Common Vervain) - A Review on the Investigations of This Medicinally Important Plant Species. Planta Med. 2020 Nov;86(17):1241-1257.

- Rehecho S, Hidalgo O, García-Iñiguez de Cirano M, Navarro I, Astiasarán I, Ansorena D, Cavero RY, Calvo MI. Chemical composition, mineral content and antioxidant activity of Verbena officinalis L. LWT – Food Sci Technol 2011; 44: 875–882.

- Potapovich AI, Kostyuk VA, Kostyuk TV, de Luca C, Korkina LG. Effects of pre- and post-treatment with plant polyphenols on human keratinocyte responses to solar UV. Inflamm Res. 2013 Aug;62(8):773-80.

- Pastore S, Potapovich A, Kostyuk V, Mariani V, Lulli D, De Luca C, Korkina L. Plant polyphenols effectively protect HaCaT cells from ultraviolet C-triggered necrosis and suppress inflammatory chemokine expression. Ann N Y Acad Sci. 2009 Aug;1171:305-13.

- Mohammed E, Grawish ME, Anees MM. Short-term effects of Verbena officinalis Linn decoction on patients suffering from chronic generalized gingivitis: Double-blind randomized controlled multicenter clinical trial. Quintessence Int (Berl) 2016; 47: 491–499.

- Dildar A, Chaudhary MA, Raza A, Waheed A, Khan SR, Ikram M. Comparative study of antibacterial activity and mineral contents of various parts of Verbena officinalis Linn. Asian J Chem 2012; 24: 68–72.

- Zhang Z, Pan T. HPLC determination of chlorogenic acid in Verbena officinalis L. extract and its in-vitro antibacterial activity. Biomed Res 2017; 28:3996–4001.

- Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Rep. 2010; 3(6):895-901.

- EMA/HMPC/55837/2011. Committee on Herbal Medicinal Products (HMPC). Assessment report on Matricaria recutita L., flos and

- Matricaria recutita L., aetheroleum.

- Gerritsen ME, Carley WW, Ranges GE, et al. Flavonoids inhibit cytokine-induced endothelial cell adhesion protein gene expression. Am J Pathol. 1995; 147(2):278-292.

- Committee on Herbal Medicinal Products (HMPC). Assessment report on Arnica montana L., flos. EMA. 6 May 2014

- Brock FE, Arnica Montana bei Venenleiden, Zeitschrift für Phytotherapie, 1991, 12, 141-145

- Brock FE, Additiver Effekt venentypischer Hydrotherapie nach Kneipp und lokaler Arnika-Anwendungen bei patienten mitvenöser Insuffizienz-Synergismus naturheilkundlicher Therapien. Fachklinik für Rehabitilation und Gefäßerkrankungen, Kneippianium, 2001; 357-363

- Seeley BM, et al. Effect of homeopathic Arnica montana on bruising in face-lifts: results of a randomized, double-blind, placebo-controlled clinical trial. Arch Facial Plast Surg. 2006; 8:54-9

- Leu S, et al. Accelerated resolution of laser-induced bruising with topical 20% arnica: a rater-blinded randomized controlled trial. Br J Dermatol. 2010; 163:557-63

- Matz H, Orion E, Wolf R. Balneotherapy in dermatology. Dermatol Ther. 2003;16(2):132-40.

- Chandrasekaran NC, Sanchez WY, Mohammed YH, Grice JE, Roberts MS, Barnard RT. Permeation of topically applied Magnesium ions through human skin is facilitated by hair follicles. Magnes Res. 2016 Jun 1;29(2):35-42.

- Chandrasekaran NC, Sanchez WY, Mohammed YH, Grice JE, Roberts MS, Barnard RT. Permeation of topically applied Magnesium ions through human skin is facilitated by hair follicles. Magnes Res. 2016 Jun 1;29(2):35-42.

- Chandrasekaran NC. Effect of topical magnesium application on epidermal integrity and barrier function. PhD Thesis, School of Chemistry and Molecular Biosciences, The University of Queensland.2016.

- Ludwig P, Petrich K, Schewe T, Diezel W. Inhibition of eicosanoid formation in human polymorphonuclear leukocytes by high concentrations of magnesium ions. Biol Chem Hoppe Seyler. 1995 Dec;376(12):739-44.

- Kramer RM, Roberts EF, Manetta J, Putnam JE. The Ca2(+)-sensitive cytosolic phospholipase A2 is a 100-kDa protein in human monoblast U937 cells. J Biol Chem. 1991 Mar 15;266(8):5268-72.

- Schempp CM, Dittmar HC, Hummler D, Simon-Haarhaus B, Schulte-Mönting J, Schöpf E, Simon JC. Magnesium ions inhibit the antigen-presenting function of human epidermal Langerhans cells in vivo and in vitro. Involvement of ATPase, HLA-DR, B7 molecules, and cytokines. J Invest Dermatol. 2000 Oct;115(4):680-6.

- Proksch E, Nissen HP, Bremgartner M, U.C., 2005. Bathing in magnesium rich Dead Sea salt improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin. International journal of dermatology, 44, pp.151–157.

- Sainte-Laudy J. Etude du pouvoir anti-degranulant de l’eau d’Avene vis-a-vis de basophiles humanis sensibilises. Int J Immunotherapy 1987: III(IV): 307.

- Bilbey DL, Prabhakaran VM. Muscle cramps and magnesium deficiency: case reports. Can Fam Physician. 1996 Jul;42:1348-51.

- Karaki H. Magnesium as a modifier of smooth muscle contractility. Microcirc Endothelium Lymphatics. 1989 Feb-Apr;5(1-2):77-97.


 
waVEN Crema Gambe - 100 ML


 
- Panahi Y, et al. Chlorella vulgaris: A Multifunctional Dietary Supplement with Diverse Medicinal Properties. Curr Pharm Des. 2016; 22:164-73.

- Del Rı́o JA,  Fuster MD,  Gómez P, Porras I, Garcı́a-Lidón A, Ortuño A. Citrus limon: a source of flavonoids of pharmaceutical interest, Food Chem. 2004;. 84(3):457-461.

- Lichota A, Gwozdzinski L, Gwozdzinski K. Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency. Eur J Med Chem. 2019; 176:68-91.

- Tejada S, Pinya S, Martorell M, et al. Potential Anti-inflammatory Effects of Hesperidin from the Genus Citrus. Curr Med Chem. 2018; 25(37):4929-4945.

- Choi IY, Kim SJ, Jeong HJ, Park SH, Song YS, Lee JH, Kang TH, Park JH, Hwang GS, Lee EJ, Hong SH, Kim HM, Um JY. Hesperidin inhibits expression of hypoxia inducible factor-1 alpha and inflammatory cytokine production from mast cells. Mol.Cell Biochem. 2007; 305:153-161.

- Zielinska-Przyjemska M, Ignatowicz E. Citrus fruit flavonoids influence on neutrophil apoptosis and oxidative metabolism. Phytother. Res. 2008; 22:1557-1562.

- Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST. The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro. Life Sci. 2007; 80(20):1821-1831.

- Nizamutdinova IT, Jeong JJ, Xu GH, et al. Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells. Int Immunopharmacol. 2008; 8(5):670-678.

- Kim SW, Kim CE, Kim MH. Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells. Biochem Biophys Res Commun. 2011; 415(4):602-607.

- Moon PD, Kim HM. Antiinflammatory effects of traditional Korean medicine, JinPi-tang and its active ingredient, hesperidin in HaCaT cells. Phytother Res. 2012; 26(5):657-662.

- Pietta P, Gardana C, Mauri P, Zecca L. High-performance liquid chromatographic analysis of flavonol glycosides of Solidago virgaurea, J of Chromatog. 1991; 558(1):296-301.

- Yang J, Guo J, Yuan J. In vitro antioxidant properties of rutin. LWT-Food Science and Technology. 2008; 41:1060-1066.

- Sthijns MMJPE, Schiffers PM, Janssen GM, et al. Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress. Biochim Biophys Acta Gen Subj. 2017; 1861(5 Pt A):1177-1189.

- Lichota A, Gwozdzinski L, Gwozdzinski K. Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency. Eur J Med Chem. 2019; 176:68-91.

- Bonaterra GA, Schwarzbach H, Kelber O, Weiser D, Kinscherf R. Anti-inflammatory effects of Phytodolor® (STW 1) and components (poplar, ash and goldenrod) on human monocytes/macrophages. Phytomedicine. 2019; 58:152868.

- Committee on Herbal Medicinal Products (HMPC). Assessment report on Ruscus aculeatus L. rhizoma. EMA, 20 November 2018

- Bouaziz N, et al. Effect of Ruscus extract and hesperidin methylchalcone on hypoxia-induced activation of endothelial cells. Int Angiol 1999, 18:306-312

- Ma L, Kou JP, Huang Y, Yu BY. Effect of ruscogenin in on adhesion of HL-60 cells to ECV304 cells. Chin Pharmacol Bull. 2006; 22:706–709

- Miller VM, et al. Interactions of Ruscus-extract with endothelin-receptors in human varicose veins. Clin Hemorheol 1994, 14: S37-S45

- Parrado F & Buzzi A. A Study of the Efficacy and Tolerability of a Preparation Containing Ruscus aculeatus in the Treatment of Chronic Venous Insufficiency of the Lower Limbs. Clinical Drug Investigation 1999; 18: 255-261

- Beltramino R, et al. An open-label, randomised multicentre study comparing the efficacy and safety of Cyclo 3 Fort versus hydroxyethyl rutoside in chronic venous lymphatic insufficiency. Angiology 2000; 51:535-544

- Rudofsky G. Efficacy of Ruscus extract in venolymphatic edema using foot volumetry. In: Vanhoute PM, ed. Return Circulation and Norepinephrine: An Update. Paris, France: John Libbey Eurotext; 1991:121-130

- Rudofsky G. Effect of Ruscus extract on the capillary filtration rate. In: Vanhoute PM, ed. Return Circulation and Norepinephrine: An Update. Paris, France: John Libbey Eurotext; 1991:219-224

- Berg D. Venous constriction by local administration of ruscus extract. Clinical Trial Fortschr Med. 1990; 108:473-6

- MA/HMPC/307782/2012. Assessment report on Eucalytus globulus Labill., Eucalyptus polybractea R.T. Baker and/or Eucalyptus smithii R.T. Baker, aetheroleum

- Dhakad AK, et al. Biological, medicinal and toxicological significance of Eucalyptus leaf essential oil: a review. J Sci Food Agric. 2018; 98: 833-848

- Azhar Sherkheli M, et al. Monoterpenoids induce agonist-specific desensitization of transient receptor potential vanilloid-3 (TRPV3) ion channels. J Pharm Pharm Sci. 2009; 12:116-28

- Nawaz A, et al. Clinical efficacy of polyherbal formulation Eezpain spray for muscular pain relief. Pak J Pharm Sci 2015; 28:43-7

- Committee on Herbal Medicinal Products (HMPC). Assessment report on Mentha x piperita L., folium and aetheroleum. EMA, 15 January 2020

- Biege M, et al. Quantity and chemical composition of essential oil of peppermint (Mentha × piperita L.) leaves under different drying methods. Int J Food Prop. 2018; 1: 267-276

- Bautista DM, et al. The menthol receptor TRPM8 is the principal detector of environmental cold. Nature. 2007; 448:204-8

- Liu B, et al. TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain. Pain. 2013; 154:2169-77

- Pergolizzi JV, et al. The role and mechanism of action of menthol in topical analgesic products. J Clin Pharm Ther. 2018; 43:313-319

- Lasanen R, et al. Menthol concentration in topical cold gel does not have significant effect on skin cooling. Skin Res Technol
. 2016; 22:40-5

- Topp R, et al. Topical menthol, ice, peripheral blood flow, and perceived discomfort. J Athl Train. 2013; 48:220-225

- Taylor R, et al. A randomized, double-blind comparison shows the addition of oxygenated glycerol triesters to topical mentholated cream for the treatment of acute musculoskeletal pain demonstrates incremental benefit over time. Pain Pract. 2012; 12:610-619

- Johar P, et al. A comparison of topical menthol to ice on pain, evoked tetanic and voluntary force during delayed onset muscle soreness. Int J Sports Phys Ther. 2012; 7:314-22

- Göbel H, et al. Essential plant oils and headache mechanisms. Phytomedicine. 1995; 2:93-102

- Garavaglia J, et al. Grape Seed Oil Compounds: Biological and Chemical Actions for Health. Nutr Metab Insights 2016; 9:59-64

- Soobrattee MA, et al. Phenolics as potential antioxidant therapeutic agents: mechanism and actions. Mutat Res. 2005; 579:200-213

- Xia EQ, et al. Biological activities of polyphenols from grapes. Int J Mol Sci. 2010; 11:622–646.

- Maffei Faccino R, et al. Free radicals scavenging action and anti-enzyme activities of procyanidines from Vitis vinifera. A mechanism for their capillary protective action. Arzneimittelforschung 1994; 44:592-601

- Wright S. Essential fatty acids and the skin: Cosmetic application of research. Br J Dermatol 1991; 125: 503-15

- Jimenez-Arnau A. Effects of Linoleic Acid Supplements on Atopic dermatitis. Adv Exp Med Biol. 1997; 433:285-7

- Duckstein SM, Stintzing FC. Investigation on the phenolic constituents in Hamamelis virginiana leaves by HPLC-DAD and LC-MS/MS. Anal Bioanal Chem. 2011 Aug; 401(2):677-88.

- Cosmetic Ingredient Review. Safety Assessment of Hamamelis virginiana (Witch Hazel)-Derived Ingredients as Used in Cosmetics. June 7, 2018.

- WHO Monographs on Selected Medicinal Plants. Folium et Cortex Hamamelidis. Vol. 2; pp. 124-136.

- Deters A, Dauer A, Schnetz E, Fartasch M, Hensel A. High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin. Phytochemistry. 2001 Nov; 58(6):949-58.

- Sorkin B. Hametumsalbe, eine kortikoidfreie antiinflammatorische Salbe. Physikalische Medizin und Rehabilitation. 1980; 21:53-57.

- Masaki H, Atsumi T, Sakurai H. Evaluation of superoxide scavenging activities of hamamelis extract and hamamelitannin. Free Radic Res Commun.1993;19(5):333-40.

- Masaki H, Atsumi T, Sakurai H. Hamamelitannin as a new potent active oxygen scavenger. Phytochemistry. 1994; 37:337-343.

- Habtemariam S. Hamamelitannin from Hamamelis virginiana inhibits the tumour necrosis factor-alpha (TNF)-induced endothelial cell death in vitro. Toxicon. 2002; 40(1):83-88.

- Moore W, James DK. A random trial of three topical analgesic agents in the treatment of episiotomy pain following instrumental vaginal delivery. Journal of Obstetrics and Gynaecology. 1989. 10:35-39.

- Diemunsch AM, Mathis C. S.T.P. Effet vasoconstricteur de l’hamamélis en application externe. Pharma; 1987. 3:111-114.


 
waVEN INTEGRATORE


- EMA/HMPC/638244/2018. Committee On Herbal Medicinal Products (HMPC). Assessment Report On Aesculus Hippocastanum L., Semen. 15 January 2020.

- Wichtl M. Testo atlante di Fitoterapia. Ed. Italiana per UTET a cura di Roberto Della Loggia. 2002.

-  Aesculus hippocastanum (Horse chestnut). Monograph. Altern Med Rev. 2009 Sep; 14(3):278-83. Review.

-  Arnould T, Janssens D, Michiels C, Remacle J. Effect of aescine on hypoxia-induced activation of human endothelial cells. Eur J Pharmacol. 1996; 315(2):227-233.

-  Montopoli M, Froldi G, Comelli MC, Prosdocimi M, Caparrotta L. Aescin protection of human vascular endothelial cells exposed to cobalt chloride mimicked hypoxia and inflammatory stimuli. Planta Med. 2007;73(3):285–288.

- Annoni F, Mauri A, Marincola F, Resele LF. Venotonic activity of escin on the human saphenous vein. Arzneimittelforschung. 1979; 29:672-675.

-  Brunner F, Hoffmann C, Schuller-Petrovic S. Responsiveness of human varicose saphenous veins to vasoactive agents. Br J Clin Pharmacol. 2001; 51(3):219–224.

-  Facino RM, Carini M, Stefani R et al. Anti-elastase and anti-hyaluronidase activities of saponins and sapogenins from Hedera helix, Aesculus hippocastanum, and Ruscus aculeatus: factors contributing to their efficacy in the treatment of venous insufficiency. Arch Pharmacol .1995; 328:720–4.

- Pittler MH, Ernst  E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database of Systematic Reviews 2012, Issue 11. Art. No.: CD003230.

- Siebert U, Brach M, Sroczynski G, Űberla K. Efficacy, routine effectiveness, and safety of horsechestnut seed extract in the treatment of chronic venous insufficiency. A meta-analysis of randomised controlled trials and large observational studies. International Angiology 2002; 21:305–315.

- Vašková J, Fejerčáková A, Mojžišová G, Vaško L, Patlevič P. Antioxidant potential of Aesculus hippocastanum extract and escin against reactive oxygen and nitrogen species. Eur Rev Med Pharmacol Sci. 2015; 19(5):879-86.

- Pirard J, Gillet P, Guffens JM, Defrance P. Double blind study of Reparil in proctology. Rev Med Liege 1976;31:343-345.

- Hitzenberger, G. Die therapeutische Wirksamkeit des Rosskastaniensamenextraktes. Wiener Medizinische Wochenschrift 1989, 139:385–389

- Schrader E, Schwankl W, Sieder C, Christoffel V. Vergleichende Untersuchung zur Bioverfügbarkeit von β-aescin nach oraler Einmalverabreichung zweier Rosskastaniensamenextrakt enthaltender, galenisch unterschiedlicher Darreichungsformen. Pharmazie 1995, 50:623–627

- Dittgen M, Zimmermann H, Wober W, Höflich C, Breitsbarth H, Timpe C. Untersuchung der Bioverfügbarkeit von β-aescin nach oraler Verabreichung verschiedener Darreichungsformen. Pharmazie 1996, 51:608–610

- Oschmann R, Biber A, Lang F, Stumpf H, Kunz K. Pharmakokinetik von β-aescin nach Gabe verschiedener Aesclus-Extrakt enthaltender Formulierungen. Pharmazie 1996, 51:577–581

- Schrödter A, Loew D, Schwankl W, Rietbrock N. Zur Validität radioimmunologisch bestimmter Bioverfügbarkeitsdaten von β-aescin in Rosskastaniensamenextrakten. Arneimittel-Forschung/Drug Research 1998, 48:905–910

- Kunz K, Lorkowski G, Petersen G, Samcova E, Schaffler K, Wauschkuhn CH. Bioavailability of escin after administration of two oral formulations containing Aesculus extract. Arzneimittel-Forschung/Drug Research 1998, 48(8):822–825

- Loew D, Schrödter A, Schwankll W, März RW. Measurement of the bioavailability of aescin-containing extracts. Methods and Findings in Experimental Clinical Pharmacology 2000, 22(7):537–542

- Liu L, Wu X, Wu D, Wang Y, Li P, Sun Y, et al. A liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of esin Ia and Ib in human plasma: application to a pharmacokinetic study after intravenous administration. Biomedical Chromatography 2010, 24:1309- 1315


 
waVEN Proctem Integratore 120ml


 
- Heggers JP, et al. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. J Altern Complement Med. 2002; 8:333-40.

- Cvetnić Z & Vladimir-Knezević S. Antimicrobial activity of grapefruit seed and pulp ethanolic extract. Acta Pharm. 2004; 54:243-50.

-  Zanotti Simões Dourado GK, et al. Orange Juice and Hesperidin Promote Differential Innate Immune Response in Macrophages ex vivo. Int J Vitam Nutr Res. 2013; 83:162–7.

-  Anti-ulcer potential of flavonoids. Indian J Physiol Pharmacol. 1998; 42:343-51.

-  Joshi R, Kulkarni YA, Wairkar S. Pharmacokinetic, pharmacodynamic and formulations aspects of Naringenin: An update. Life Sci. 2018; 215:43-56.

-  Xu H, Kulkarni KH, Singh R, et al. Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides. Mol Pharm. 2009;6(6):1703-1715.

- Strauch K, Lutz U, Bittner N, Lutz WK. Dose-response relationship for the pharmacokinetic interaction of grapefruit juice with dextromethorphan investigated by human urinary metabolite profiles. Food Chem Toxicol. 2009 Aug;47(8):1928-35.

- Al-Snafi A. Medical importance of Cupressus sempervirens-A review. IOSR J Pharm. 2016; 6. 66-76

- Khan MF, Ahamad T, Rawat P. Biomedicinal and Chemical Profile of Cupressus sempervirens: A Mini Review. Insights in Biomedicine. 2017; 02(03).

- Wen L, Zhang Z, Sun DW, Sivagnanam SP, Tiwari BK. Combination of emerging technologies for the extraction of bioactive compounds. Crit Rev Food Sci Nutr. 2020;60(11):1826-1841.

- Vardanega R, Santos DT, Meireles MA. Intensification of bioactive compounds extraction from medicinal plants using ultrasonic irradiation. Pharmacogn Rev. 2014 Jul;8(16):88-95.

- Tiwari BK. Ultrasound: A clean, green extraction technology. TrAC Trends in Analytical Chemistry. 2015; 71, 100–109.

- Chemat F, Rombaut N, Sicaire AG, Meullemiestre A, Fabiano-Tixier AS, Abert-Vian M. Ultrasound assisted extraction of food and natural products. Mechanisms, techniques, combinations, protocols and applications. A review. Ultrason Sonochem. 2017 Jan;34:540-560.

- Asgary S, Naderi GA, Shams Ardekani MR, Sahebkar A, Airin A, Aslani S, Kasher T, Emami SA. Chemical analysis and biological activities of Cupressus sempervirens var. horizontalis essential oils. Pharm Biol. 2013 Feb; 51(2):137-44.

- Ben Nouri A, Dhifi W, Bellili S, Ghazghazi H, Aouadhi C, Chérif A, Hammami M, Mnif W. Chemical Composition, Antioxidant Potential, and Antibacterial Activity of Essential Oil Cones of Tunisian Cupressus sempervirens. J Chem. 2015; Article ID 538929, 8 pages.

- Mascolo N, Autore G, Capasso F, Menghini A, Fasulo MP. Biological screening of Italian medicinal plants for anti-inflammatory activity. Phytotherapy Res. 1987; 1(1), 28–31.

- Piovetti L, Gonzalez E, Diara A. Diterpene composition of Cupressus dupreziana and Cupressus sempervirens. Phytochemistry. 1980; 19:2772-2773. 12

- Al-Snafi A. Medical importance of Cupressus sempervirens-A review. IOSR J Pharm. 2016; 6. 66-76

- Khan MF, Ahamad T, Rawat P. Biomedicinal and Chemical Profile of Cupressus sempervirens: A Mini Review. Insights in Biomedicine. 2017; 02(03).

- Zouaghi N, Bellel C, Cavaleiro C, Nadjemi B, Yousfi M. Identification of volatile compounds, antimicrobial properties and antioxidant activity from leaves, cones and stems of Cupressus sempervirens from Algeria. Afr J Microbiol Res. 2015; 9:83-90.

- Toroglu S. In vitro antimicrobial activity and antagonistic effect of essential oils from plant species. J Environ Biol. 2007 Jul; 28(3):551-9.

- Nielsen SE, Young JF, Daneshvar B, Lauridsen ST, Knuthsen P, Sandstrom B, Dragsted LO. Effect of parsley (Petroselinum crispum) intake on urinary apigenin excretion, blood antioxidant enzymes and bio-markers for oxidative stress in human subjects. Br. J. Nutr. 1999; 81, 447–455.

- Shimoi K, Okada H, Kaneko J, Furugori M, Goda T, Takase S, Suzuki M, Hara Y, Kinae N. Bioavailability and antioxidant properties of luteolin. Natural Antioxidants and Anticarcinogens in Nutrition, Health and Disease (The Royal Society of Chemistry, Cambridge, UK). 1999;167–173.

- Manach C, Donovan JL. Pharmacokinetics and metabolism of dietary flavonoids in humans. Free Radic Res. 2004 Aug;38(8):771-85.

- Schmidt L, Göen T. Human metabolism of α-pinene and metabolite kinetics after oral administration. Arch Toxicol. 2017 Feb;91(2):677-687.

- Kimura Y, Ito H, Ohnishi R, Hatano T. Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity. Food Chem Toxicol. 2010 Jan;48(1):429-35.

- Ruiz-Ruiz JC, Moguel-Ordoñez YB, Segura-Campos MR. Biological activity of Stevia rebaudiana Bertoni and their relationship to health. Crit Rev Food Sci Nutr. 2017 Aug 13;57(12):2680-2690.

- Myint KZ, Wu K, Xia Y, Fan Y, Shen J, Zhang P, Gu J. Polyphenols from Stevia rebaudiana (Bertoni) leaves and their functional properties. J Food Sci. 2020 Feb;85(2):240-248.

- Bender C, Graziano S, Zimmermann BF. Study of Stevia rebaudiana Bertoni antioxidant activities and cellular properties. Int J Food Sci Nutr. 2015;66(5):553-8.

- Salehi B, López MD, Martínez-López S, Victoriano M, Sharifi-Rad J, Martorell M, F Rodrigues C, Martins N. Stevia rebaudiana Bertoni bioactive effects: From in vivo to clinical trials towards future therapeutic approaches. Phytother Res. 2019 Nov;33(11):2904-2917.
 
 


waVEN GSE PROCTEM POMATA 40 ml


 
- European Medicines Agency Evaluation of Medicines for Human Use. Assessment report on Althaea officinalis L. Radix.Doc. Ref.: MEA/HMPC/98718/2008. London, 14 May 2009.

- Franz G. Polysaccharides in pharmacy: current applications and future concepts. Planta Med 1989; 55:493-7.

- Deters A, Zippel J, Hellenbrand N, Pappai D, Possemeyer C, Hensel A. Aqueous extracts and polysaccharides from Marshmallow roots (Althea officinalis L.): cellular internalisation and stimulation of cell physiology of human epithelial cells in vitro. J Ethnopharmacol. 2010 Jan 8;127(1):62-9.

-  Sendker J, Böker I, Lengers I, Brandt S, Jose J, Stark T, Hofmann T, Fink C, Abdel-Aziz H, Hensel A. Phytochemical Characterization of Low Molecular Weight Constituents from Marshmallow Roots (Althaea officinalis) and Inhibiting Effects of the Aqueous Extract on Human Hyaluronidase-1. J Nat Prod. 2017 Feb 24;80(2):290-297.

-  Curnow A, Owen SJ. An Evaluation of Root Phytochemicals Derived from Althea officinalis (Marshmallow) and Astragalus membranaceus as Potential Natural Components of UV Protecting Dermatological Formulations. Oxid Med Cell Longev. 2016;2016:7053897.

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waVEN GSE PROCT-EM SALI DI EPSOM 300 g


 
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waVen Relief Oil


 
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- Malekuti J, et al. Comparison of the effect of Myrtus communis herbal and anti-hemorrhoid ointments on the hemorrhoid symptoms and quality of life in postpartum women with grade I and II internal hemorrhoid: A triple-blinded randomized controlled clinical trial. J Complement Integr Med. 2019: 20180147

- Ebrahimabadi EH, et al. Combination of GC/FID/mass spectrometry fingerprints and multivariate calibration techniques for recognition of antimicrobial constituents of Myrtus communis L. essential oil. J Chromatogr B Analyt Technol Biomed Life Sci. 2016; 1008:50-57

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