Bibliografia Linea Allergy

ALLERBRON BIOSTERINE^® FIALE

- Stansbury j. Et al, “Rosmarinic acid as a novel agent in the treatment of Allergies and Asthma” J. Restorative Medicine, 2014; Osakabe N. et al.” Anti-inflammatory and anti-allergic effect of Rosmarinic acid (RA); inhibition of seasonal allergic rhinoconjunctivitis (SAR) and its mechanism”, Biofactors, 2004; Mondal S. et al. “Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum L.) leaf extract on healthy volunteers” J Ethnopharmacol, 2011. Jongsung Lee et al. “Rosmarinic acid as a downstream inhibitor of IKK-b in TNF-a-induced regulation of CCL11 and CCR3”, British Journal of Pharmacology, 2006.

- Tabart et al. “Antioxidant and anti-inflammatory activities of Ribes nigrum extracts”, Food Chemistry 131, 2012; EMA “Assesment Report on Ribes nigrum L., folium, 2010; A. Gopalan et al., “The health benefits of blackcurrants”, Royal Society of Chemistry, Food and Function, 2012.

- R González-Sánchez et al, “Forskolin versus Sodium Cromoglycate for Prevention of Asthma Attacks: a Single-blinded Clinical Trial” The Journal of International Medical Research, 2006.

- Kumar A.,“Medicinal uses and pharmacological activity of Adhatoda vasica”, Int. J. Herbal Medicine, 2014.

- Kenji Fukushima et al, “Drosera rotundifolia and Drosera tokaiensis suppress the activation of HMC-1 human mast cells”, Journal of Ethnopharmacology 125, 2009.

- Macchi, P. et al., Clinica di Otorinolaringoiatria, Università dell’Insubria, Varese, “Gli effetti del sodio ialuronato nei bambini con infezioni ricorrenti delle alte vie respiratorie: risultati di uno studio randomizzato controllato” International Journal of Immunopathology and Pharmacology, Vol 26, n°1, ,2013. G. Petrigni, L. Allegra, “Aerosolised hyaluronic acid prevents exercise-induced bronchoconstriction, suggesting novel hypotheses on the correction of matrix defects in asthma” Pulmonary Pharmacology & Therapeutics 19, 2006.

ALLERBRON BIOSTERINE^® JUNIOR

- R González-Sánchez et al, “Forskolin versus Sodium Cromoglycate for Prevention of Asthma Attacks: a Single-blinded Clinical Trial” The Journal of International Medical Research, 2006.

- Kumar A.,“Medicinal uses and pharmacological activity of Adhatoda vasica”, Int. J. Herbal Medicine, 2014.
5. Kenji Fukushima et al, “Drosera rotundifolia and Drosera tokaiensis suppress the activation of HMC-1 human mast cells”, Journal of Ethnopharmacology 125, 2009.

BIOSTERINE^® ALLERGY AREMEDY

- Alimentazione e Fitoterapia, Alessandro Formenti, Tecniche Nuove, 2016

- L’uomo, la fitoterapia, la gemmoterapia, B. Brigo. Tecniche Nuove, 2009

- M. Cohen et al, Tulsi-Ocimum sanctum: a herb for all reasons. Journal of Ayurveda & Integrative Medicine, 2014

- S. Mondal et al, Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum L.) leaf extract on healthy volunteers. Journal of Ethnopharmacology, 2011

- M.A. Kelm et al, Antioxidant and cyclooxygenase inhibitory phenolic compounds from Ocimum sanctum L. Phytomedicine, 2000.

- Singh et al, Biological activities of Ocimum sanctum L. fixed oil-an overview. Indian J. Exp. Biol. 45, 403–412.

- Arvind Sahu et al, Inhibition of Complement by Covalent Attachment of Rosmarinic Acid to Activated C3b, Biochemical Pharmacology, Vol. 57, pp. 1439–1446, 1999

- C. Colica et al, Rosmarinic Acid as Potential Anti-Inflammatory Agent, Reviews on Recent Clinical Trials, 2018, 13, 240-242

- Ahmad Ghorbani et al, Pharmacological properties of Salvia officinalis and its components, Journal of Traditional and Complementary Medicine 7 (2017)

- Hubbert M, Sievers H, Lehnfeld R, Kehrl W. Efficacy and tolerability of a spray with Salvia officinalis in the treatment of acute pharyngitis e a randomised, double-blind, placebo-controlled study with adaptive design and interim analysis. Eur J Med Res. 2006

- Naomi Osakabe et al, Anti-inflammatory and anti-allergic effect of rosmarinic acid (RA); inhibition of seasonal allergic rhinoconjunctivitis (SAR) and its mechanism, BioFactors, Volume 21, Issue 1-4, pages 127–131, 2004

- J. Stansbury et al, Rosmarinic acid as a novel agent in the treatment of allergies and asthma. Journal of Restorative Medicine 2014.

- J. Lee et al, Rosmarinic acid as a downstream inhibitor of IKK-b in TNF-a-induced upregulation of CCL11 and CCR3. British Journal of Pharmacology (2006)

- Katsunari lppoUSHI et al, Evaluation of Inhibitory Effects of Vegetables and Herbs on Hyaluronidase and ldentification of Rosmarinic Acid as a Hyaluronidase Inhibitor in Lemon Balm (Melissa officinalis L.), FoodSci. Technol Res., 6 ( I). 74-77. 2000

- Baba S, et al. Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla frutescens extract in humans. Eur J Nutr. 2005; 44:1-9

- Noguchi-Shinohara M, et al. Pharmacokinetics, Safety and Tolerability of Melissa officinalis Extract which Contained Rosmarinic Acid in Healthy Individuals: A Randomized Controlled Trial. PLoS One. 2015

- Z. Krajcovicova et al, Bioactivity and potential health benefits of rosmarinic acid. University Review, 2013

- Sang-Bum Kim et al, Metabolic interactions of rosmarinic acid with human cytochrome P450 monooxygenases and uridine diphosphate glucuronosyltransferases, Biomed Pharmacotherapy, 2019

- Ashwin Gopalan et al. The health benefits of blackcurrants. Food & Function, 2012

- EMA/HMPC/142989/2009. Assessment report on Ribes nigrum L., folium, 2010

- J. Tabart et al, Antioxidant and anti-inflammatory activities of Ribes nigrum extracts. Food Chemistry, 2012

- Anette Karlsen et al, Anthocyanins Inhibit Nuclear Factor-kB Activation in Monocytes and Reduce Plasma Concentrations of Pro-Inflammatory Mediators in Healthy Adults. J. Nutr. 137: 1951–1954, 2007

- Teresa Röhrig et al, Absorption of Anthocyanin Rutinosides after Consumption of a Blackcurrant (Ribes nigrum L.) Extract. J. Agric. Food Chem. 2019

- Adom MB, et al. Chemical constituents and medical benefits of Plantago major. Biomed Pharmacother. 2017; 96:348-360

- Genc Y, et al. The inhibitory effects of isolated constituents from Plantago major subsp. major L. on collagenase, elastase and hyaluronidase enzymes: Potential wound healer. Saudi Pharm J. 2020; 28:101-106

- Najafian Y, et al. Plantago major in Traditional Persian Medicine and modern phytotherapy: a narrative review. Electron Physician. 2018; 10:6390-6399

- Ringbom T, et al. Ursolic acid from Plantago major, a selective inhibitor of cyclooxygenase-2 catalyzed prostaglandin biosynthesis. J Nat Prod. 1998; 61:1212-5

- Samuelsen AB. The traditional uses, chemical constituents and biological activities of Plantago major L. A review. J Ethnopharmacol. 2000; 71:1-21

- Chiang LC, et al. In vitro cytotoxic, antiviral and immunomodulatory effects of Plantago major and Plantago asiatica. Am J Chin Med. 2003; 31:225-34

- L. Chiang et al. Immunomodulatory activity of flavonoids, monoterpenoids, triterpenoids, iridoid glycosides and phanolic compound of Plantago Species. Planta Med, 2003

- Zeng et al. A review of the pharmacology and toxicology of aucubin. Fitoterapia, 2019.

- EMA/HMPC/437858/2010 Community herbal monograph on Plantago lanceolata L., folium. 25 November 2010

- Sheldon S. Hendler, PDR, Physicians’ desk reference, CEC Editore, 2010.

- Robert J Nijveldt et al, Flavonoids: a review of probable mechanisms of action and potential applications. Am J Clin Nutr 2001

- Shoskes DA. Effect of bioflavonoids quercetin and curcumin on ischemic renal injury: a new class of renoprotective agents. Transplantation.1998;66:147–52.

- Sorata Y, Takahama U, Kimura M. Protective effect of quercetin and rutin on photosensitized lysis of human erythrocytes in the presence of hematoporphyrin. Biochim Biophys Acta 1984.

- Hyo-Hyun Park. Flavonoids Inhibit Histamine Release and Expression of Proinflammatory Cytokines in Mast Cells. Arch Pharm Res Vol 31, No 10, 1303-1311, 2008

- M. Kimata. Effect of luteolin, quercetin, baicalein, on Immunoglobulin-E mediator release from human cultured mast cells. Clinical and Experimental Allergy, 2000.

- Madhavan P.N. Nair et al. The flavonoid, quercetin, differentially regulates Th-1 (IFNg) and Th-2 (IL4) cytokine gene expression by normal peripheral blood mononuclear cells. Biochimica et Biophysica Acta 1593 (2002)

- Mol Nutr Food Res. 2018 Jan. Safety Aspects of the Use of Quercetin as a Dietary Supplement. Andres S, Pevny S, Ziegenhagen R, Bakhiya N, Schäfer B, Hirsch-Ernst KI, Lampen A.

- Morteza Jafarinia et al, Quercetin with the potential effect on allergic diseases. Allergy Asthma Clin Immunol (2020)

- Gianluigi Marseglia, Amelia Licari et al. A polycentric, randomized, parallel-group, study on Lertal®, a multicomponent nutraceutical, as preventive treatment in children with allergic rhinoconjunctivitis: phase II. Italian Journal of Pediatrics (2019) 45:84

- Marcin Oharowski et al. Pharmacological Effect of Quercetin in Hypertension and Its Potential Application in Pregnancy-Induced Hypertension: Review of In Vitro, In Vivo, and Clinical Studies. Evidence-Based Complementary and Alternative Medicine, 2018

- Jiri Mlcek et al. Quercetin and Its Anti-Allergic Immune Response. Molecules 2016

- Sheldon S. Hendler, PDR, Physicians’ desk reference, CEC Editore, 2010.

- Robert J Nijveldt et al, Flavonoids: a review of probable mechanisms of action and potential applications. Am J Clin Nutr 2001

- Hollman P.C. et al. Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man. FEBS Lett. 1997

- Hanasaki Y. et al. The correlation between active oxygen scavenging and antioxidative effects of flavonoids. Free Radic Biol Med. 1994

- Yoo H et al. Anti-inflammatory effects of rutin on HMGB1-induced inflammatory responses in vitro and in vivo. Inflamm Res. 2014

- Jung CH et al. Anti-asthmatic action of quercetin and rutin in conscious guinea-pigs challenged with aerosolized ovalbumin. Arch Pharm Res. 2007

- Kim HY et al. Protective effects of rutin through regulation of vascular endothelial growth factor in allergic rhinitis. Am J Rhinol Allergy. 2015

- A A Bamigboye, R. Smyth et al. Interventions for varicose veins and leg oedema in pregnancy. Cochrane Database Syst Rev. 2015

BIOSTERINE^® ALLERGY AREMEDY JUNIOR

- Shakeri A, et al. Melissa officinalis L. – A review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol. 2016; 188:204-28

- Miraj S, et al. Melissa officinalis L: a review study with an antioxidant prospective. J Evid Based Complementary Altern Med. 2017; 22:385-394

- Mimica-Dukic N, et al. Antimicrobial and antioxidant activities of Melissa officinalis L. (Lamiaceae) essential oil. J Agric Food Chem. 2004; 52:2485-9

- Geuenich S, et al. Aqueous extracts from peppermint, sage and lemon balm leaves display potent anti-HIV-1 activity by increasing the virion density. Retrovirology 2008; 5:27

- Astani A, et al. Melissa officinalis extract inhibits attachment of herpes simplex virus in vitro. Chemotherapy. 2012; 58:70-7

- Chen SG, et al. Anti-enterovirus 71 activities of Melissa officinalis extract and its biologically active constituent rosmarinic acid. Sci Rep. 2017; 7:12264

- Martins EN, et al. Protective effect of Melissa officinalis aqueous extract against Mn-induced oxidative stress in chronically exposed mice. Brain Res Bull. 2012; 87:74-9

- Moacă EA, et al. A comparative study of Melissa officinalis lLeaves and stems ethanolic extracts in terms of antioxidant, cytotoxic, and antiproliferative potential. Evid Based Complement Alternat Med. 2018; 2018:7860456

- Guginski G, et al. Mechanisms involved in the antinociception caused by ethanolic extract obtained from the leaves of Melissa officinalis (lemon balm) in mice. Pharmacol Biochem Behav. 2009; 93:10-6

- Hasanein P & Riahi H. Antinociceptive and antihyperglycemic effects of Melissa officinalis essential oil in an experimental model of diabetes. Med Princ Pract. 2015; 24:47-52

- Sforcin JM, et al. Lemongrass effects on IL-1beta and IL-6 production by macrophages. Nat Prod Res. 2009; 23:1151-9

- La Rocca V, et al. Geraniol Induces Antinociceptive Effect in Mice Evaluated in Behavioural and Electrophysiological Models. Basic Clin Pharmacol Toxicol. 2017; 120:22-29

- Savino F, et al. A randomized double-blind placebo-controlled trial of a standardized extract of Matricariae recutita, Foeniculum vulgare and Melissa officinalis (ColiMil) in the treatment of breastfed colicky infants. Phytother Res. 2005; 19:335-40

- Müller SF & Klement S. A combination of valerian and lemon balm is effective in the treatment of restlessness and dyssomnia in children. Phytomedicine. 2006; 13:383-7

- Gromball J, et al. Hyperactivity, concentration difficulties and impulsiveness improve during seven weeks' treatment with valerian root and lemon balm extracts in primary school children. Phytomedicine. 2014; 21: 1098-103

- Kennedy DO, et al. Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm). Psychosom Med. 2004; 66:607-13

- Cases J, et al. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances. Med J Nutrition Metab. 2011; 4:211-218

- Tavares-Silva C, et al. Homeopathic medicine of Melissa officinalis combined or not with Phytolacca decandra in the treatment of possible sleep bruxism in children: A crossover randomized triple-blinded controlled clinical trial. Phytomedicine. 2019; 58:152869

- Haybar H, et al. The effects of Melissa officinalis supplementation on depression, anxiety, stress, and sleep disorder in patients with chronic stable angina. Clin Nutr ESPEN. 2018; 26:47-52

- Zeraatpishe A, et al. Effects of Melissa officinalis L. on oxidative status and DNA damage in subjects exposed to long-term low-dose ionizing radiation. Toxicol Ind Health. 2011; 27:205-12

- Wölbling RH & Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine. 1994; 1:25-31

- Karousou R, et al. "Mints", smells and traditional uses in Thessaloniki (Greece) and other Mediterranean countries. J Ethnopharmacol. 2007; 109:248-57

- Anwar F, et al. Mentha: A genus rich in vital nutra-pharmaceuticals-A review. Phytother Res. 2019; 33:2548-2570

- Mahboubi M. Mentha spicata as natural analgesia for treatment of pain in osteoarthritis patients. Complement Ther Clin Pract. 2017; 26:1-4

- Petersen M & Simmonds MS. Rosmarinic acid. Phytochemistry. 2003; 62:121-5

- Vejdani R, et al. The efficacy of an herbal medicine, Carmint, on the relief of abdominal pain and bloating in patients with irritable bowel syndrome: a pilot study. Dig Dis Sci. 2006; 51:1501-7

- Connelly AE, et al. High-rosmarinic acid spearmint tea in the management of knee osteoarthritis symptoms. J Med Food. 2014; 17:1361-7

- Herrlinger KA, et al. Spearmint extract improves working memory in men and women with age-associated memory impairment. J Altern Complement Med. 2018; 24:37-47

- Lasrado A, et al. Safety and tolerability of a dried aqueous spearmint extract. Regul Toxicol Pharmacol. 2017; 86:167-176

- Falcone PH, et al. The attention-enhancing effects of spearmint extract supplementation in healthy men and women: a randomized, double-blind, placebo-controlled, parallel trial. Nutr Res. 2019; 64:24-38

- Shahbazi Y. Chemical composition and In Vitro antibacterial activity of Mentha spicata essential oil against common food-borne pathogenic bacteria. J Pathog. 2015; 2015:916305

- Snoussi M, et al. Mentha spicata essential oil: chemical composition, antioxidant and antibacterial activities against planktonic and biofilm cultures of Vibrio spp. Strains. Molecules. 2015; 20:14402-24

- Wiwattanarattanabut K, et al. In vitro anti-cariogenic plaque effects of essential oils extracted from culinary herbs. J Clin Diagn Res. 2017; 11:DC30-DC35

- Stringaro A, et al. Antioxidant, antifungal, antibiofilm, and cytotoxic activities of Mentha spp. essential oils. Medicines. 2018; 5(4). pii: E112.

- Hu Z, et al. Antioxidant effect of aromatic volatiles emitted by Lavandula dentata, Mentha spicata, and M. piperita on mouse subjected to low oxygen condition. Biosci Biotechnol Biochem. 2017; 81:2386-2395

- Ben Saad A, et al. Protective effects of Mentha spicata against nicotine-induced toxicity in liver and erythrocytes of Wistar rats. Appl Physiol Nutr Metab. 2018; 43:77-83

- Mogosan C, et al. a comparative analysis of the chemical composition, anti-inflammatory, and antinociceptive effects of the essential oils from three species of Mentha cultivated in Romania. Molecules. 2017; 22(2). pii: E263

- Direito R, et al. Reduction of inflammation and colon injury by a spearmint phenolic extract in experimental bowel disease in mice. Medicines 2019;6(2). pii: E65

- Caro DC, et al. Pharmacological evaluation of Mentha spicata l. and Plantago major l., medicinal plants used to treat anxiety and insomnia in colombian caribbean coast. Evid Based Complement Alternat Med. 2018; 2018:5921514

- Sadeghi Ataabadi M, et al. Role of essential oil of Mentha Spicata (Spearmint) in addressing reverse hormonal and folliculogenesis disturbances in a Polycystic Ovarian Syndrome in a rat model. Adv Pharm Bull. 2017 Dec;7(4):651-654

- Naomi Osakabe et al., Anti-inflammatory and anti-allergic effect of rosmarinic acid (RA); inhibition of seasonal allergic rhinoconjunctivitis (SAR) and its mechanism, BioFactors, Volume 21, Issue 1-4, pages 127–131, 2004.

- J. Stansbury et al., Rosmarinic acid as a novel agent in the treatment of allergies and asthma. Journal of Restorative Medicine 2014.

- J. Lee et al., Rosmarinic acid as a downstream inhibitor of IKK-b in TNF-a-induced upregulation of CCL11 and CCR3. British Journal of Pharmacology (2006)

- Katsunari lppoUSHI et al., Evaluation of Inhibitory Effects of Vegetables and Herbs on Hyaluronidase and ldentification of Rosmarinic Acid as a Hyaluronidase Inhibitor in Lemon Balm (Melissa officinalis L.), FoodSci. Technol Res., 6 ( I). 74-77. 2000

- Baba S, et al. Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla frutescens extract in humans. Eur J Nutr. 2005; 44:1-9

- Z. Krajcovicova et al., Bioactivity and potential health benefits of rosmarinic acid. University Review, 2013.

- Sang-Bum Kim et al., Metabolic interactions of rosmarinic acid with human cytochrome P450 monooxygenases and uridine diphosphate glucuronosyltransferases, Biomed Pharmacotherapy, 2019.

- Ashwin Gopalan et al. The health benefits of blackcurrants. Food & Function, 2012

- EMA/HMPC/142989/2009. Assessment report on Ribes nigrum L., folium, 2010

- J. Tabart et al., Antioxidant and anti-inflammatory activities of Ribes nigrum extracts. Food Chemistry, 2012

- Anette Karlsen et al., Anthocyanins Inhibit Nuclear Factor-kB Activation in Monocytes and Reduce Plasma Concentrations of Pro-Inflammatory Mediators in Healthy Adults. J. Nutr. 137: 1951–1954, 2007

- Teresa Röhrig et al., Absorption of Anthocyanin Rutinosides after Consumption of a Blackcurrant (Ribes nigrum L.) Extract. J. Agric. Food Chem. 2019