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Symptoms and relief

Our purpose is not to hinder the physiological processes of the organism. Ours is a holistic approach. An approach that encourages the ristoring of the physical balance, by facing the causes as efficiently as possible and by ensuring a fast relief of all the symptoms.



Stomach and intestine

A good diet and an efficient digestive process are essential to be in good health because we are what we eat, but most of all, we are what we manage to absorb. Long term good health depends on healthy nutrition, on an adequate digestive process and assimilation of foodstuffs; over time, gastric problems and incomplete digestive processes lead to several chronic disorders (gastritis, reflux, constipation, meteorism, occasional diarrhea) and other serious diseases (food intolerances, diseases from immune-complex deposition, liver overloaded with toxins, etc.). The primary function of the gastrointestinal system is to dismantle complex molecules so that nutrients deriving from foodstuffs, which would not be usable or absorbable at native state, are made bioavailable. Gastric and intestinal problems are very widespread.

Inflammations and damage of the gastrointestinal mucosa, responsible for the insurgence of gastritis and ulcers, affect large groups of people: around 70% of adults frequently experience heartburn and 50% of people aged over 45 suffer from chronic gastritis; moreover, 10% of the population, especially those aged between 30 and 50, show clinical signs of peptic ulcer, single or multiple. Intestinal dysbiosis is, on the other hand, at the origin of the most diverse health problems, ranging from Candida to an unbalanced immune system that can lead to frequent illnesses, several disorders of the intestine, food intolerances, etc.

Hyperacidity, heartburn and digestive difficulties are all symptoms showing gastric discomfort, a problem unfortunately affecting around 70% of adults; in 50% of subjects aged over 45, chronic gastritis and even much more serious consequences are possible (10% of the population aged between 30 and 50 presents signs of peptic ulcer).

These symptoms, involving the upper digestive tract, may originate for different reasons, according to the subject. However, regardless of the triggering factor, what actually underlies the problem is the inability of the gastric mucosa to maintain the balance between “aggressive” factors (gastric juices and digestive enzymes) and “protective” factors (prostaglandins 2, secretion of alkaline mucous, etc.).

Dominance of the former over the latter, in fact, triggers the gradual lesion of gastric wall layers, leading to slight or slight to medium-level typical symptoms initially, later developing into gastritis and then ulcers located in the stomach and duodenum.

The principal factor triggering hyperacidity, heartburn, difficult digestion, etc. is stress, linked to a hectic lifestyle, often coupled with an unhealthy diet. Helicobacter Pylori is another major factor responsible for gastric symptoms: the bacteria, present in 90% cases of gastritis and in 70% ulcers, colonises the mucosa, mechanically destroying its protective coating, thereby exposing it to the corrosive action of gastric juice.

Abuse of aspirin and other anti-inflammatories is also associated to heartburn and hyperacidity, involving a significant risk of incurring in gastritis and ulcers. In fact, these drugs exert their anti-inflammatory action by inhibiting the synthesis of prostaglandins. Prostaglandins are a family of molecules , naturally present in our organism and divided into two distinct groups: pro-inflammatory prostaglandins, responsible for many symptoms related to the inflammatory status, and gastroprotective prostaglandins, which settle along the stomach walls, protecting it from the corrosive action of gastric acids.

Non-selective inhibition of this family of compounds entails that synthesis of pro inflammatory prostaglandins is inhibited, thereby obtaining the desired anti-inflammatory effect through the medicine itself; yet, at the same time synthesis of protective prostaglandins is also inhibited, the result of which being that the mucosa itself, now deprived of its natural defenses, is exposed to the action of digestive juices, risking lesions and ulcerations.

Treatment of hyperacidity, heartburn and difficult digestion with conventional medicine

Given the spread of gastric disorders, it is clear that the number of “conventional” remedies to treat the disorder is fairly high. There are, in fact, several medicines classified as “antiulcers”, the principal ones being antiacids, proton-pump inhibitors and H2 – antagonists.

However, as often happens with official medicine, the method adopted to solve the pathology causes serious negative effects on the patient’s organism.

Antiacid medicines: these are mainly Aluminium Salts, Calcium, Sodium and Magnesium, which react with Hydrochloric acid produced by the stomach, thereby neutralizing acidity in excess; these are symptomatic medicines and therefore eliminating only the symptoms related to the increased acidity without actually acting on the root causes. Despite their being widely used, an ideal antiacid medicine has not yet been discovered: there are many side-effects possible, particularly related to the presence of the above mentioned metals, which consumers know well enough about.
Surely, the principle element responsible for side effects of antiacid medicines is Aluminium: usually present as “Aluminium hydroxide”, it causes disorders in several anatomical districts. It has, in fact, been proven that Aluminium weakens tissues in the digestive tract: it “kidnaps” vitamins and other nutrients, inactivating them and making them unusable by the organism, besides causing constipation and other intestinal disorders. Morever, the excessive intake of Aluminium can cause symptoms of poisoning such as constipation, colic, loss of appetite, nausea, dermatological disorders, muscular spasms in the lower limbs, excessive perspiration and loss of energy.

At any rate, main side effects caused by this metal can go far beyond what one might think: as a matter of fact, researchers have found out that one of the most widely used forms of Aluminium as an antiacid, namely Aluminium Hydroxide gel, can reduce the level of phosphate in the bloodstream, causing bone dissolution, pain and muscular weakness. Frequent ingestion of the metal reduces bone mass and diminishes matrix and bone formation. But this is not all: small quantities of soluble Alumium salts in the blood slowly cause poisoning, characterized by motor paralysis and numbness in certains parts of the body, with a degeneration of kidneys and liver. Anatomical changes in nervous centres, as well as symptoms of gastrointestinal inflammation may also appear. All these symptoms are the outcome of the body’s efforts to eliminate the poison.

Morevoer, Aluminium is strongly involved in certain behavioural disorders: in fact, aluminium ions easily settle on body fat and in the brain, causing disorders in the Central Nervous System; in the long run, this situation can cause the insurgence of pathologies such as saturnism and mood swings; in addition, it has recently been highlighted that infinitesimal quantities of Aluminium in the brain are connected to epileptic seizures, senile dementia, convulsions and Alzheimer disease.

Sodium, too, bears negative effects, involving different body districts: the first and foremost harmful effect is surely water retention, with symptoms ranging from superficial skin imperfections, to much more serious problems such as hypertension. Other side effects are systemic alkalosis, constipation or diarrhea, belching, “acid refluxes” due to hyperneutralisation of gastric acidity resulting in recovery of the gastric mucosa’s secretory activity, which can cause an increase in the level of acidity of the stomach’s pH.

Proton pump inhibiting medicines (PPI): these are anti-ulcer medicines par excellence, usually prescribed initially in all cases of heartburn and gastritis. Their mechanism of action provides for the irreversible block of the so-called protonic pump producing hydrochloric acid, but not only: in fact, proton pump inhibitors block the acid secretion induced by gastrin and this, in turn, causes an increased secretion of gastrin itself, which leads to hypergastrinemia.
High levels of gastrin can cause hyperplasia of cells in the gastric fundus containing histamine. In the animal world, hyperplasia has often developed into gastric carcinoma. Apart from presenting numerous side-effects, these widely used medicines markedly alter digestive processes, with disastrous consequences at gastrointestinal level.

It has moreover been highlighted that proton pump inhibitors interfere with the absorption of calcium and vitamins (besides medicines) and are responsible for the heightened risk of hip fractures: hence, they are harmful when it comes to safeguarding the skeleton’s integrity.

H2 Antagonist medicines: these molecules inhibit gastric acid secretion induced by histamine and, to a lesser extent, secretion mediated by gastrin and Acetylcholine. H2 antagonists inhibit basal and nocturnal acid secretion, as well as secretions stimulated by food. However, side-effects generated by these medicines are all but minor: H2 Antagonists, in fact, have an antiandrogenic effect that can cause gynecomastia (growth of breasts in men) and impotence; moreover, certain molecules in particular have shown negative effects on the central nervous system, such as anxiety, panic, mental confusion and memory lapses.
The most significaticant side effect, however, regards the ability of these medicines to inhibit P450 Cytochrome. This leads to other medicines previously taken remaining longer in the bloodstream, with ensuing, heightened toxic effects.

What’s needed, therefore, is an entirely different approach, aiming to solve the problem rapidly, yet without interfering with physiological digestive mechanisms,while maintaining efficiency and balance of the entire digestive tract.

Nature can help you in case of hyperacidity, heartburn and difficult digestion

A natural and effective approach

In cases of gastric discomfort (hyperacidity, heartburn and difficult digestion), it is essential to act on the symptoms, solving them rapidly and completely, yet without undermining the stomach’s physiological functionality – that is to say, without leaving the gastric mucosa in a condition of imbalance between “protective” and “aggressive” factors, ensuring that symptoms do not degenerate to the point of causing gastritis and ulcers.

GSE and hyperacidity, heartburn and difficult digestion

Grapefruit Seed Extract (GSE), well-known for its antibacterial, antifungal, antiviral and parasiticidal properties, recognized by Laboratories and Institutes worldwide, has been recently employed by a group of researchers at the Jagiellonian University Medical College in Krakow (Poland), with the aim of studying its potential properties with particular reference to the protection of the gastrointestinal mucosa. Studies have confirmed the researchers’ hypotheses, highlighting both GSE’s gastroprotective role, as well as its ability to accelerate wound healing.

GSE’s mechanisms of action have been shown to be as follows: activation of the endogenous synthesis of prostaglandins, the expression of mucous cell growth factors, suppression of oxidative stress and an increase of submucosal bloodstream. These discoveries, together with the well-known antibacterial properties towards Helicobacter Pylori, intensify the protective and reparative action of Grapefruit Seed Extract towards the gastric mucosa.

Its use is absolutely safe, particularly because its activity has no impact whatsoever on the microbial intestinal flora while safeguarding the organism’s natural defenses, as confirmed by a study published in the “Journal of Orthomolecular Medicine”, Volume 5 Nr. 3 of 1990,

For the above-mentioned reasons, GSE therefore represents the cornerstone of an extremely effective approach to handle gastric discomfort. Its association and synergy with specific plant extracts enables:

  1. Action at gastric level with a dual purpose: on the one hand, aiding digestion, acting on dyspepsia and soothing heartburn and hyperacidity; on the other, directly contrasting contamination of H. Pylori where present;
  2. Action on hyperacidity, calming inflammation, soothing pain and promoting the remedying of damaged gastroesophageal mucosa.

This approach, combined with a healthy lifestyle (in terms of diet, but not only), includes the use of natural remedies that are well known in folk tradition and the efficacy of which in providing a definitive solution has been confirmed by recent studies.

1 - Action at gastric level with a dual purpose: on the one hand, aiding digestion, acting on dyspepsia and soothing heartburn and hyperacidity; on the other, directly contrasting contamination of H. Pylori where present:
Nature can help you with…

Grapefruit Seed Extract: direct antibiotic action against H. Pylori, present in 90% of cases of gastritis, hence indirectly on other gastric symptoms. GSE moreover offers gastroprotective and reparative action on the gastric mucosa. As an intestinal “selective cleanser”, it eliminates pathogenic microorganisms while fully respecting physiological bacterial flora.

Pineapple: an actual digestif; this feature is mainly due to the presence of bromelain, an enzyme with a marked proteolytic action, i.e. apt for digesting proteins.

Cardamom: traditionally employed to cure stomach ache and to promote digestion, is has undoubted eupeptic, stimulant, stomachic and, mostly, carminative properties.

Coriander: an excellent antidiarrhoeal, it seeds also have extraordinary digestive properties.

Cumin: it contains carvone and limonene terpenes, which help regulate gastrointestinal functionality, stimulating gastric secretion and alleviate any pain or abdominal cramps thanks to their antispasmodic activity.

Rhubarb: in small doses, this drug acts as a stomachic and bitter tonic, stimulating secretions and gastric motility, thereby facilitating digestive processes.

Milk thistle: it stimulates the appetite, but most of all if promotes digestion. In addition, it is an excellent antispasmodic.

The ideal means for intake of the above-mentioned plant ingredients, ideal to restore balance of physiological functions in the digestive tract, is represented by swallowable tablets.

Action on hyperacidity, calming inflammation, soothing pain and promoting the remedying of damaged gastroesophageal mucosa:
Nature can help you with…

Grapefruit Seed Extract: Grapefruit Seed Extract (GSE), well-known for its antimicrobial properties, recognized by Laboratories and Institutes worldwide, has been recently employed by a group of researchers at the Jagiellonian University Medical College in Krakow (Poland), with the aim of studying its potential properties with particular reference to the protection of the gastrointestinal mucosa.

As already mentioned, studies have confirmed the researchers’ hypotheses, highlighting both the gastroprotective role of Grapefruit Seed Extract, as well as its ability to accelerate healing processes. These discoveries, together with the well-known antibacterial properties towards Helicobacter Pylori, intensify GSE’s protective and reparative action towards the gastric mucosa.

Centella: scientific studies have confirmed the value of traditional uses of this plant as a cicatrising and vascular-protective agent, highlighting its marked properties when it comes to the restructuring and regeneration of the connective tissue. Through the stimulation of fibroblasts, Centella induces the synthesis of both the constituents making up connective tissue, namely glycosaminoglycans, as well as collagen and elastin, thereby accelerating the wound healing processes.

In case of ulcers and gastritis, Centella can be a precious ally as it helps restructure and reinforce the gastrointestinale mucous barrier, in order to protect itself from harm caused by aggressive factors and in order to accelerate the healing of lesions.

Laurel: its leaves and fruits are rich in pectins; when hydrated they adhere to the stomach walls, increasing its resistance against both endogenous and exogenous, harmful agents.

Lythrum salicaria: it owes its name to lythron, meaning blood clot, a testimony to its well-known antihemorrhagic properties. The synergic action of the phytocomplex’s active principles solves the inflammatory state of the gastro-intestinal mucosa and promotes haemostasis of lesions, preventing hemorrhagic complications.

Rutin: a flavonoid with marked vascular-protective, antioxidant and re-epithelising properties, thanks to which is supports and accelerates cicatrizing propertis of inflamed or damaged mucosae.

Boswellia: with marked anti-inflammatory properties, unlike typical synthetic anti-inflammatories (NSAIMs), it does not cause gastric intolerance; on the contrary, it shows protective action towards ulcers and gastritis.

Passiflora: well-known for its sedative and calming properties. Given the relevance of factors such as stress and anxiety in the insurgence of ulcers and gastritis, Passiflora is particularly suitable. Moreover, its recognized efficacy in alleviating gastrointestinal spasms enable to obtain a pain-killing effect. Its extract is beneficial in the treatment of anxiety and nervousness, without running the risk of addiction.

In such cases, it is advisable to take plant active constituents contained in swallowable tablets to be ingested on an empty stomach so as to facilitate direct action on the mucosa: one tablet around mid-morning, another at mid-afternoon and a third one before going to bed.

Since, as already mentioned, heartburn can often cause damage and lesions on the gastroesophageal mucosa, it may be necessary to apply long-term treatment, so as to gradually restructure and restore physiological functionality of the mucosae.