A natural and effective approach
Juvenile acne is a problem primarily caused by a hormonal change typical of puberty, determining a number of transformations involving the skin, as well, such as vestigial follicules turning into pilosebacious follicules, particularly at face and torso level; additionally, there is an increased production of sebum and a change in its composition, as it becomes enriched with free fatty acids which are irritants for the skin.
Moreover, several factors contribute to the problem, connected to the particular lifestyle adopted (nutritional lifestyle and stress factors), which influence the triggering off and progression of the disorder. Hence, it is necessary to take action with specific natural products, both at systemic and at local level, so as to uproot all the causes leading to this affection.
GSE and juvenile acne
Regarding the the efficacy of Grapefruit Seed Extract (GSE) as a broad spectrum antimicrobial, Laboratories and Institutes worldwide have proven that GSE is active against over 800 bacterial strains (both Gram+ and Gram-), as well as against countless viruses and over 100 strains of yiests and moulds. Numerous testimonies confirm its validity and in terms of both efficacy and speed of action it remains unrivalled in nature. These features, together with the even more unique characteristic of not having a negative impact on intestinal microbial flora, as confirmed by a study published in the “Journal of Orthomolecular Medicine” Vol. 5 n°3, 1990, make it a really extraordinary remedy to control proliferation of pathogenic and/or opportunistic microorganisms.
The importance of having a healthy and balanced intestinal microflora has already been highlighted, particularly with regard to its role in preserving the balance and efficiency of the immune system and to ensure adequate defense of the organism against any kind of microbial infection. Moreover, also when applied in formulations for local use, due to its “selective cleansing” action it acts against pathogens without significantly affecting the physiological flora of skin and mucosae, safeguarding their essential, defensive functionality.
GSE therefore represents an extremely valuable aid in solving the problem of juvenile acne.
Given the above considerations, GSE therefore represents the cornerstone of a really effective and complete approach to handle the problem of acne, that provides for the following:
1) Systemic action, contrasting genetic, hormonal, intestinal and anxiogenic factors representing causes and concauses of the problem of acne;
2) Local action on the skin with a treatment formulated to regulate androgenic activity and production of sebum in the area affected; contrasting P.acnes in a specific way, by carrying out a delicately exfoliating, keratolytic action, tightening dilated pores, while reducing acneic lesion and promoting cicatrisation;
3) Cleanse the skin using a specific product capable of exerting antimicrobial and purifying action, while fully respecting the hydrolipidic film.
This approach, combined with a healthy lifestyle (in terms of diet, but not only), includes the use of natural remedies that are well known in folk tradition and the efficacy of which in providing a definitive solution has been confirmed by recent studies.
- Systemic action, contrasting genetic, hormonal, intestinal and anxiogenic factors representing causes and concauses of the problem of acne
Nature can help you with…
Grapefruit Seed Extract : GSE is a valuable aid, thanks to its important, scientifically proven and acknowledged broad spectrum antibacterial and antiseptic properties. At systemic level, it destroys pathogenic microorganisms responsible for spreading toxins inside the organism and triggering acne and skin impurities (it is a well-known fact that toxins alter hormonal balance).
At the same time, it maintains the intestine’s bacterial flora in good health, helping it to carry out its purifying and protective role.
Sage: a plant belonging to the Labiatae family, it is an evergreen shrub with aromatic properties and grows wildly in the Mediterranean Basin. Parts used are the leaves and flowers, from which an essential oil is obtained as well as active ingredients, the most important of which are: alpha and beta-thujone, alpha and beta-pinene, limonene, camphor, cineol, borneol, etc.; phenolic acid (rosmarinic acid, chlorogenic acid, caffeic acid); bitter principles (salvin, picrosalvin); flavonoids, glucosides of apigenin and luteolin; triterpenes, diterpenes, etc.
Sage carries out an important purifying and decongestant action thanks to its choleretic and cholagogue action, in which flavonoids play a key role; it is antispasmodic and a bitter tonic stimulant in dyspeptic forms and in gastro-intestinal atony, particularly in subjects that are fatigued both physically and intellectually. It has proven antihydrotic properties (reducing perspiration), mainly due to an essential oil that is capable of inhibiting the activity of sweat glands,by acting on nerve endings.
Sage essential oil offers an antiseptic/antimicrobial action, mainly owing to thujone and cineol terpenes and it also plays a role as a hormonal regulator, acting on the hypothalamus –hypophysis – adrenal glands and ovaries axis; in addition, it contains phytoestrogens, antagonizing the hypersecretion of androgens (male hormones), thereby controlling sebaceous secretion.
Thanks to the presence of these estrogenic fractions, Sage is an emmenagogue as well, in that is regulates the menstrual flux and is useful in calming painful disorders linked to the menopause. It exerts an anti-inflammatory action on the oral cavity.
Turmeric: it belongs to Zingiberaceae family (including Ginger), native to India and Indonesia. A perennial herbaceous plant, characterized by the typical orange-yellow rhizomes that reaches up to 60 cm in depth.
The aerial part reaches about 90 cm, with broad leaves and a yellow-white, spike-shaped flower. Turmeric is well known for its use in the food industry, as it is the main constituent of Indian Curry. The plant’s rhizome, from which the main active ingredients are obtained, called curcuminoids, is used for health purposes.
Turmeric is a very important herb in Ayurvedic medicine, that considers it as as a “cleansing” herb, beneficial for the whole body. In fact, it is one of the most important and well-known cholagogues and choleretics: it simulates the production and secretion of bile from the pancreas (increasing the production of bile acids by over 100%) and acts as a eukinetic (regularising movement) on the gall bladder, thereby enhancing digestive processes, particularly the emulsion of fat and its absorption.
Moreover, it optimises hepatic functionality and has a hepatoprotective action, mainly due to its antioxidant power. Finally, it carries out an anti-inflammatory action – also at topical level, as well as being an effective antimicrobial against several bacteria and pathogenic fungi.
Viola tricolor: it belongs to the Violaceae family and the whole plant and its flowers are employed for health purposes, owing to its being particularly rich in constituents, mainly: mucilages, flavonoids (among which rutin), saponin, carotenoids, tannins and salicylic derivatives. In particular, owing to the presence of flavonoids, it carries out a purifying activity on the skin and is diuretic; as an antiseborrhoeic, it contrasts the hypersecretion of sebaceous glands, therefore making it particularly active in suppurative and exudative forms (from acne to seborrhaeic eczema)
It moreover acts as a general purifier, since it is capable of strengthening the detoxifying activity of excretory organs such as liver, kidneys, intestine and skin and is particularly suitable for the drainage and purification of the blood. The presence of mucilages makes it excellent as an expectorant, an emollient of bronchial secretions and anti-tussient.
Rhubarb: a plant belonging to the Polygonaceae family, native to China. In phytotherapy the roots are used, out of which the following active constituents are extracted: anthraquinone glucosides, polyphenols, pectins and sennosides.
At low doses, these plant extracts are digestive, as they stimulate the secretion of gastric juices, excretion of bile from the liver and normal peristalsis of the digestive tract; whereas at high doses it is a laxative plant due to the presence of anthraquinone glucosides, causing reduced absorption of liquids at colon level that tend to accumulate in the intestinal lumen, generating a laxative effect.
Among plants containing anthraquinones, Rhubarb is the most tolerated one owing to the presence of polyphenols, with its proven anti-inflammatory activity not to be found in other anthraquinone plants, while limiting side-effects which are, on the other hand, to be expected following intake of Senna, Frangula and Cascar. Rhubarb is recommended when other plants are no longer effective and is better tolerated compared to Senna. Taken at ideal doses, it is therefore slightly laxative and it moreover purifies the bile due to its essential actions which are choleretic and cholagogue, promoting bile flow and expelling bile waste material through the intestine: for this reason it is particularly active on irritative, inflamed and suppurative cutaneous affections.
Passiflora: a deciduous herbaceous plant native to the South-East area of the United States. Active ingredients are extracted from its flowers (alkaloids, harmala, passiflorine, apigenin, luteolin, quercetin, phytosterols, phenolic acids, coumarin, glycosides, cyanogenics, traces of essential oils, flavonoids, vitexin, isovitexin, saponaria, rutin, quercetin, etc.); among these, harmala alkaloids, together with flavonoids, exert a spasmolytic action, mostly usable at bronchial level, whereas flavonoids (isovitexin) and coumarins (maltol) provide a sedative action.
The plant’s activity is essentially sedative, antispasmodic, indicated in sleeping disorders and in case of anxiety, neurosis and distress; it stimulates physiological sleep without night awakenings or numbness in the morning; it proves useful for menopause disorders such as tachycardia, dyspnea, hot flashes, stress. It relaxes the smooth muscular tissues of the digestive tract and is therefore an excellent antispasmodic, beneficial for digestive processes. It is also indicated in cases of menstrual pain as it relaxes the muscles of the uterine wall and helps relieve pain. Passiflora carries out a beneficial action on the central nervous system because of its mild soothing-sedative effect, without producting narcotic or depressive effects.
Therefore, for a general relaxing and antispasmodic, mildly hypnotic effect, its presence is essential to break the vicious circle caused by anxiety, typical of subjects affected by acne. Effects on the central nervous system are rapid and do not lead to undesired effects.
Vitamins A and E: these are beneficial vitamins for the skin, useful for their strengthening and nourishing action.
The ideal means to convey all these ingredients is a swallowable tablet.
- Local action on the skin with a treatment formulated to regulate androgenic activity and production of sebum in the area affected; contrasting P.acnes in a specific way, by carrying out a delicately exfoliating, keratolytic action, tightening dilated pores, reducing acneic lesion and promoting cicatrisation;
Nature can help you with…
Grapefruit Seed Extract: Grapefruit Seed Extract, well-known for its broad spectrum antimicrobial properties, has proven to be effective also against P. acnes, which colonises acneic lesions. Including GSE in a topical remedy aimed at solving the problem of acne is therefore essential to ensure selective disinfection of the skin, while fully respecting physiological flora.
Usnea barbata: a lichen also referred to as “old man’s beard”, it is known to have excellent antiviral and antibiotic power and has recently been tested also tested on P. acnes. Certain studies on the efficacy of this lichen for topical use against this specific disorder have shown a remarkable increase of activities in association with the phytocomplex of Hypericum.
Hypericum: an officinal plant of the Hypericum genus, also called St. John’s wort, its essential oil has anti-inflammatory properties for the skin, a fact which has been well- known as far back as the Middle Ages, when oily extracts of this plant were used to soothe and reduce inflammatory conditions of skin featuring reddening and scars. These specific activites are attributable to the significant presence of flavonoids in the phytocomplex.
Calendula officinalis: the herbalist tradition has handed down its use for topical preparations aimed at the resolution of cutaneous and non cutaneous inflammations. Today, modern phytotherapy recognizes the soothing and anti-inflammatory activity of the calendula phytocomples, as well as its being a stimulant of tissue regeneration, mainly due to the presence of triterpene glycosides.
Cucurbita pepo: pumpkin seeds, rich in essential fatty acids, have shown extraordinary efficacy in the treatment of acneic lesions. Their recognized anti-androgenic, anti-inflammatory properties together with their activity in regulating the production of sebum greatly improve the skin’s aspect, reducing the typical “shiny effect”.
Marsdenia condurango: the bark of this tree of tropical origin presents a phytocomplex that is rich in tannins, providing it with a marked astringent activity, particularly useful in “closing” pores dilated by sebum. It moreover adds a cicatrizing and reepithelising property, stimulating the reparative process of the cutaneous tissue.
These vegetable functionals can easily be conveyed in a cream, ideal for morning treatment.
Nature can help you with…
Estratto di semi di Pompelmo: Grapefruit Seed Extract, well-known for its broad spectrum antimicrobial properties, has proven to be effective also against P. acnes, which colonises acneic lesions. Including GSE in a topical remedy aimed at solving the problem of acne is therefore essential to ensure selective disinfection of the skin, while fully respecting physiological flora.
Krameria trianda (Rhatany): a plant well known for its astringent properties, it has recently been tested as an antimicrobial, yielding excellent results: in fact the lipophilic extract of Rhatany has proven to be effective on several bacterial strains responsible for the infection of acneic lesions, reducing their presence on the skin by 50% in only one week.
Salvia sclarea: a herbaceous, fragrant plant belonging to the Lamiaceae family, with recognised extrogen-like activity, besided being relaxing and mildly sedative, necessary in case of extrogen-like action required to rebalance hormonal activity.
Serenoa repens: the phytocomplex of this dwarf palm has proven to be effective in inhibiting 5α-reductase, an enzyme that generates hydrotestosterone, responsible for the appearance of acne.
Centella asiatica: the phytocomplex of this officinal plant belongs to the family of Apiaceae and has been one of the most studied plants during the past decade: its being particularly rich in active ingredients makes the plant well recognized for its health properties, particularly related to its anti-inflammatory activity.
Among its main constituents is the family of asiaticosides, triterpenes showing such activity in vivo and in vitro, besides an anti-reddening and reepithelising activity, surely useful in case of acne.
Azelaic acid: extracted from vegetable sources, it has shown keratolytic properties in several in vitro and in vivo studies, ideal for the treatment of acneic acid. In addition, it has been proven that this substances reduces sebaceous secretions, while exerting antimicrobial and anti-inflammatory activites at the same time.
Hibiscus (Hybiscus sabdariffa): a tropical flower of the Malvaceae family, it is rich in pyruvic acid, used in skin disorders. Its actions are mainly focused at epidermic level, where it carries out a keratolytic action, reducing the adherence between keratinocytes and therefore of skin thickness; at dermis level it stimulates the formation of collagen, glycoproteins and elastic fibres. Moreover, hibiscus exerts an anti-inflammatory and soothing activity.
These plant ingredients are easily conveyed in a cream which is ideal for evening treatment.
- Cleanse the skin using a specific product capable of exerting antimicrobial and purifying action, while fully respecting the hydrolipidic film.
Nature can help you with…
Grapefruit Seed Extract: recognised as a natural antimicrobial par excellence. It has proven to be active against countless bacterial strains, among which P. acnes, and can therefore be defined as the ideal antimicrobial to contrast infections from acneic lesions.
Burdock (Arctium lappa): mentioned in the “Herbarium Apulei”, Burdoch has been employed since ancient times as a remedy to solve several problems. Modern phytotherapy recognizes its marked antimicrobial activity, attributable to the presence of different sesquiterpene lactones in the phytocomplex. Moreover, its purifying properties are beneficial for topical use; the diaphoretic activity of the phytocomplex encourages purification of the pores, therefore particularly useful in the treatment of acne.
Melaleuca alternifolia: the oil extracted from this plant, better known under the name of Tea Tree Oil, has proven antiseptic properties on a vast range of bacterial and fungal strains. In particular, its use as a cutaneous antimicrobial has shown great efficacy in different disorders, among which acne.
These plant ingredients are conveyed in a cleansing milk that is free from aggressive excipients, enriched by the presence of olive oil and glycerine of plant origin.